Changes in Tissue Oxygenation Following Regional Anesthesia
Adequate tissue oxygenation is required for effective white blood cell function and bactericidal activity. Decreased tissue oxygenation is a risk factor for perioperative wound infections. Regional anesthetic techniques result in a functional sympathetic block and may increase tissue oxygenation. The purpose of this study is to evaluate changes in tissue oxygenation using a non-invasive Near-infrared spectroscopy (NIRS) device. The current study will evaluate changes in tissue oxygenation following regional anesthetic techniques (peripheral nerve blockade and neuraxial techniques such as caudal block) in pediatric patients).
Regional anesthesia will induce a sympathetic blockade and improve tissue oxygenation.
Cases Requiring a Regional Anesthetic.
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||Changes in Tissue Oxygenation Following Regional Anesthesia|
- Tissue oxygenation [ Time Frame: 1 Day (Day of Surgery) ] [ Designated as safety issue: No ]NIRS values from two sites before and after the regional anesthetic is placed.
|Study Start Date:||September 2011|
|Study Completion Date:||June 2012|
|Primary Completion Date:||April 2012 (Final data collection date for primary outcome measure)|
|Non-invasive near infra-red device (NIRS)|