Changes in the Permeability of the Blood Brain Barrier and Intestinal Barrier in Humans During Conditions of Stress and Immune Activation: in Vivo Studies

This study has been completed.
Sponsor:
Information provided by:
National University Hospital, Singapore
ClinicalTrials.gov Identifier:
NCT01417416
First received: August 15, 2011
Last updated: NA
Last verified: February 2009
History: No changes posted
  Purpose

The relevance of BBB and IB permeability changes as a major precipitating cause for cognitive and digestive dysfunction in the military stress setting.


Condition
Combat Training Stress

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective

Further study details as provided by National University Hospital, Singapore:

Groups/Cohorts
with combat training stress
without combat training stress

  Eligibility

Ages Eligible for Study:   18 Years to 50 Years
Genders Eligible for Study:   Male
Sampling Method:   Probability Sample
Study Population

Healthy male troops during combat training

Criteria

Inclusion Criteria:

  • Healthy male troops (aged 18-50 yrs) scheduled to be engaged in a protracted multi-day stressful field exercises.

Exclusion Criteria:

  • Significantly systemic disease, including cardiovascular, psychiatric, neurological (including polyneuropathies) and endocrine disease including diabetes mellitus.
  • No written informed consent obtained from subject.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

No Contacts or Locations Provided
  More Information

No publications provided

ClinicalTrials.gov Identifier: NCT01417416     History of Changes
Other Study ID Numbers: C/08/236, DSOCL08210
Study First Received: August 15, 2011
Last Updated: August 15, 2011
Health Authority: Singapore: Domain Specific Review Boards

ClinicalTrials.gov processed this record on July 29, 2014