Physical Activity in Postmenopausal Women

This study has been completed.
Sponsor:
Information provided by:
National Taiwan University Hospital
ClinicalTrials.gov Identifier:
NCT01398605
First received: July 14, 2011
Last updated: August 16, 2011
Last verified: July 2011
  Purpose

The study is designed to investigate the physical activity and its dose-response relationship in postmenopausal women on the cardiovascular risks and cardiac function.


Condition Intervention
Postmenopausal Disorder
Other: Exercise training

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Official Title: Physical Activity and Exercise Dose-response on Cardiovascular Risk Factors in Postmenopausal Women

Resource links provided by NLM:


Further study details as provided by National Taiwan University Hospital:

Primary Outcome Measures:
  • Body mass index (BMI) [ Time Frame: 3 months ] [ Designated as safety issue: No ]
  • Waist circumference [ Time Frame: 3 months ] [ Designated as safety issue: No ]
  • Lab data (lipid profile, CRP, insulin resistance) [ Time Frame: 3 months ] [ Designated as safety issue: No ]
  • QT interval and corrected QT interval (QTc) [ Time Frame: 3 months ] [ Designated as safety issue: No ]
  • Cardiovascular fitness [ Time Frame: 3 months ] [ Designated as safety issue: No ]
  • Heart rate recovery after exercise test [ Time Frame: 3 months ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • Myocardial perfusion [ Designated as safety issue: No ]

Estimated Enrollment: 200
Study Start Date: September 2008
Study Completion Date: July 2010
Primary Completion Date: July 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: moderate exercise training Other: Exercise training
Different dose of exercise training
Experimental: intensive exercise training Other: Exercise training
Different dose of exercise training
No Intervention: Control

  Eligibility

Ages Eligible for Study:   40 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Postmenopausal women aged 40 to 80 years and age matched men without major diseases

Exclusion Criteria:

  • Known cardiac disease, excessive weight change during last year, cancer and mental disorders
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01398605

Locations
Taiwan
National Taiwan University Hospital
Taipei, Taiwan
Sponsors and Collaborators
National Taiwan University Hospital
Investigators
Principal Investigator: Ying-Tai Wu, PhD National Taiwan University Hospital
  More Information

No publications provided

Responsible Party: Ying-Tai Wu, School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University
ClinicalTrials.gov Identifier: NCT01398605     History of Changes
Other Study ID Numbers: 200709026R
Study First Received: July 14, 2011
Last Updated: August 16, 2011
Health Authority: Taiwan: Department of Health

Keywords provided by National Taiwan University Hospital:
Postmenopausal women
Physical activity
Cardiovascular risks
Cardiac function
Dose-response

ClinicalTrials.gov processed this record on September 18, 2014