Functional MRI and MRA in Migraine With Aura

The recruitment status of this study is unknown because the information has not been verified recently.
Verified May 2011 by Glostrup University Hospital, Copenhagen.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Glostrup University Hospital, Copenhagen
ClinicalTrials.gov Identifier:
NCT01388894
First received: July 5, 2011
Last updated: NA
Last verified: May 2011
History: No changes posted
  Purpose

Patients who report that exposure to bright light or strenuous physical activity will induce migraine aura will be provoked using one or both of these methods. Followingly the patients will be examined by functional MRI. Íf the patients develop migraine headache, MR angiography will be performed as well. The primary study hypothesis is that the functional MRI signal will show features similar to those of the electrophysiological phenomenon of cortical spreading depression.


Condition
Migraine With Aura

Study Type: Observational
Study Design: Observational Model: Case-Crossover
Time Perspective: Prospective
Official Title: Functional MRI and MRA in Migraine With Aura

Resource links provided by NLM:


Further study details as provided by Glostrup University Hospital, Copenhagen:

Estimated Enrollment: 80
Study Start Date: December 2010
  Eligibility

Ages Eligible for Study:   18 Years to 80 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Patients diagnosed with migraine with aura

Criteria

Inclusion Criteria:

  • Diagnosed with migraine with aura as defined by The International Classification of Headache Disorders 2
  • Age between 18 and 80 years both inclusive
  • Reports that bright light or strenuous physical activity may trigger migraine aura

Exclusion Criteria:

  • Contraindications towards exposure to photostimulation or strenuous exercise
  • Body weight above 130 kg
  • Pregnant or lactating females
  • Contraindications towards MRI scanning
  • History or clinical signs of: cardiovascular disease, psychiatric disease, substance abuse or any symptom or disease considered relevant by the examining physician.
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01388894

Contacts
Contact: Anders Hougaard, MD +4538632713 andhou05@glo.regionh.dk

Locations
Denmark
Danish Headache Center Recruiting
Glostrup, Denmark, 2600
Contact: Anders Hougaard, MD    +4538632713    andhou05@glo.regionh.dk   
Sub-Investigator: Anders Hougaard, MD         
Sponsors and Collaborators
Glostrup University Hospital, Copenhagen
  More Information

No publications provided

Responsible Party: Jes Olesen, Danish Headache Center
ClinicalTrials.gov Identifier: NCT01388894     History of Changes
Other Study ID Numbers: MA-01
Study First Received: July 5, 2011
Last Updated: July 5, 2011
Health Authority: Denmark: The Regional Committee on Biomedical Research Ethics
Denmark: Danish Dataprotection Agency

Additional relevant MeSH terms:
Migraine Disorders
Migraine with Aura
Brain Diseases
Central Nervous System Diseases
Headache Disorders
Headache Disorders, Primary
Nervous System Diseases

ClinicalTrials.gov processed this record on October 29, 2014