Outcomes Following Phacoemulsification With 1.8 & 2.2mm Incision: Randomized Clinical Trial

• Ingress of Trypan blue from the Ocular Surface into the Anterior Chamber [ Time Frame: Immediately at the end of surgery ] [ Designated as safety issue: No ]
  At end of surgery, stromal hydration of all incisions will be performed.0.0125% trypan blue will be instilled on the conjunctival surface.After 2 minutes, the surface will be irrigated with balanced salt solution. 0.1ml aqeous aspirate will be obtained from the anterior chamber.Concentration of trypan blue in the aspirate will be ascertained by UV visible spectrophotometry. Log dilutions of concentration of trypan blue will be used for statistical analysis
  
  

• Surgically Induced Astigmatism [ Time Frame: At baseline and 3 months postoperatively ] [ Designated as safety issue: No ]
  
• Corneal Endothelial Cell Loss [ Time Frame: Baseline and 3 months postoperatively ] [ Designated as safety issue: No ]
  
• Change in Central Corneal Thickness [ Time Frame: Baseline and 1 week ] [ Designated as safety issue: No ]
  
• Anterior Chamber Inflammation [ Time Frame: Baseline and 1 week ] [ Designated as safety issue: No ]
  
• Anterior Chamber Inflammation [ Time Frame: Baseline and 1 month ] [ Designated as safety issue: No ]
  

Cataract surgical techniques have significantly changed in recent years with the widespread adoption of smaller and smaller clear corneal incisions for phacoemulsification. Microincision surgery has many advantages, including reduced surgically induced astigmatism, faster visual recovery, and reduced intra and postoperative inflammation. In the recent times, microcoaxial phacoemulsification has gained popularity. The main advantage of this newer technique is that it uses the same methods as the conventional method but with smaller incisions. Curently, microcoaxial phacoemulsification is being performed through 1.8 as well as 2.2 mm incisions. However, there is still a debate as to which is the best absolute incision size for microcoaxial cataract surgery.

The aim of this study is to evaluate incision stability following microcoaxial phacoemulsification performed through 1.8 and 2.2 mm systems, as well as compare intraoperative performance and postoperative outcomes following microcoaxial phacoemulsification performed through these two incision sizes.