Protocol to Obtain Blood and Bone Marrow Samples for Myeloma Research
The purpose of this study is to collect a blood or bone marrow sample from patients with multiple myeloma and from volunteers without myeloma.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Evaluation of Immune Parameters and Function in Multiple Myeloma Patients and Healthy Individuals' Blood and Marrow Samples|
- Cancer cell response to molecular testing of killing cell parts. [ Time Frame: 2 Years ] [ Designated as safety issue: No ]This myeloma specific killing may help identify mechanisms, in vitro, of killing myeloma cells for the future use in clinical trials.
Biospecimen Retention: Samples With DNA
15mL of peripheral blood 10mL of bone marrow aspirate
|Study Start Date:||August 2010|
|Estimated Study Completion Date:||December 2014|
|Estimated Primary Completion Date:||December 2014 (Final data collection date for primary outcome measure)|
Healthy volunteers who have agreed to have a bone marrow and/or blood harvest as part of a donation to a transplant recipient.
Patients with multiple myeloma
Patients undergoing routine blood draw and bone marrow aspirates as part of their ongoing follow-up care for myeloma at the Norris Cotton Cancer Center of DHMC.
The blood and bone marrow samples will be used in the laboratory to perform focused studies on multiple myeloma.
|United States, New Hampshire|
|Dartmouth-Hitchcock Medical Center|
|Lebanon, New Hampshire, United States, 03756|
|Principal Investigator:||Kenneth Meehan, MD||Dartmouth-Hitchcock Medical Center|