Protocol to Obtain Blood and Bone Marrow Samples for Myeloma Research
The purpose of this study is to collect a blood or bone marrow sample from patients with multiple myeloma and from volunteers without myeloma.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Evaluation of Immune Parameters and Function in Multiple Myeloma Patients and Healthy Individuals' Blood and Marrow Samples|
- Cancer cell response to molecular testing of killing cell parts. [ Time Frame: 2 Years ] [ Designated as safety issue: No ]This myeloma specific killing may help identify mechanisms, in vitro, of killing myeloma cells for the future use in clinical trials.
Biospecimen Retention: Samples With DNA
15mL of peripheral blood 10mL of bone marrow aspirate
|Study Start Date:||August 2010|
|Estimated Study Completion Date:||December 2014|
|Estimated Primary Completion Date:||December 2014 (Final data collection date for primary outcome measure)|
Healthy volunteers who have agreed to have a bone marrow and/or blood harvest as part of a donation to a transplant recipient.
Patients with multiple myeloma
Patients undergoing routine blood draw and bone marrow aspirates as part of their ongoing follow-up care for myeloma at the Norris Cotton Cancer Center of DHMC.
The blood and bone marrow samples will be used in the laboratory to perform focused studies on multiple myeloma.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01382615
|United States, New Hampshire|
|Dartmouth-Hitchcock Medical Center|
|Lebanon, New Hampshire, United States, 03756|
|Principal Investigator:||Kenneth Meehan, MD||Dartmouth-Hitchcock Medical Center|