The Observational Study of Growth Hormone-secreting Pituitary Tumors

This study is currently recruiting participants.
Verified September 2013 by Huashan Hospital
Sponsor:
Collaborator:
National Natural Science Foundation of China
Information provided by (Responsible Party):
Zhaoyun Zhang, Huashan Hospital
ClinicalTrials.gov Identifier:
NCT01368133
First received: June 6, 2011
Last updated: September 24, 2013
Last verified: September 2013
  Purpose

The major purpose of this study is to evaluate the changes of multiple organs in patients with growth hormone-secreting pituitary tumors before and after surgery. Plasma, DNA samples and pituitary tumor tissues will be kept for further analysis.


Condition
Acromegaly
Pituitary Tumor

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Observational Study of the Structures and Functions of Multiple Organs in Patients With Growth Hormone-secreting Tumors

Resource links provided by NLM:


Further study details as provided by Huashan Hospital:

Biospecimen Retention:   Samples With DNA

Plasma, DNA and pituitary tumor tissues


Estimated Enrollment: 60
Study Start Date: May 2011
Estimated Study Completion Date: December 2013
Estimated Primary Completion Date: December 2013 (Final data collection date for primary outcome measure)
Detailed Description:

Multiple organs or systems will be affected by excessive growth hormones in patients with acromegaly. The major purpose of this study is to evaluate the changes before and after the pituitary surgery.

  Eligibility

Ages Eligible for Study:   18 Years to 70 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population

The acromegaly patients at Huashan Hospital will be recruited anf followed up prior to surgery and one month, 3 months, 6 months and 12 months after surgery.

Criteria

Inclusion Criteria:

  • Clinical diagnosis of acromegaly
  • > 18 years old
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01368133

Contacts
Contact: Jiahui Qiu, M.D. 86-13585951850 qiuhuijiaatsjtu@163.com
Contact: zhaoyun zhang, M.D. 86-21-52888286 zhaoyunzhang@fudan.edu.cn

Locations
China
Huashan Hospital Recruiting
Shanghai, China, 200040
Contact: Cuiyun Wu    86-21-52888047    hskyc@fudan.edu.cn   
Contact: Zhaoyun Zhang    86-21-52888286    zhaoyunzhang@fudan.edu.cn   
Principal Investigator: Yao Zhao, M.D.         
Sponsors and Collaborators
Huashan Hospital
National Natural Science Foundation of China
Investigators
Principal Investigator: Yao Zhao, M.D. Huashan Hospital
  More Information

No publications provided

Responsible Party: Zhaoyun Zhang, Associate Professor, Huashan Hospital
ClinicalTrials.gov Identifier: NCT01368133     History of Changes
Other Study ID Numbers: 2010M-010
Study First Received: June 6, 2011
Last Updated: September 24, 2013
Health Authority: China: Food and Drug Administration

Keywords provided by Huashan Hospital:
acromegaly
pituitary tumor

Additional relevant MeSH terms:
Pituitary Neoplasms
Pituitary Diseases
Endocrine Gland Neoplasms
Neoplasms by Site
Neoplasms
Hypothalamic Neoplasms
Supratentorial Neoplasms
Brain Neoplasms
Central Nervous System Neoplasms
Nervous System Neoplasms
Acromegaly
Bone Diseases, Endocrine
Bone Diseases
Musculoskeletal Diseases
Hyperpituitarism
Hypothalamic Diseases
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Endocrine System Diseases
Hormones
Hormones, Hormone Substitutes, and Hormone Antagonists
Physiological Effects of Drugs
Pharmacologic Actions

ClinicalTrials.gov processed this record on April 17, 2014