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The Effect of the Duty Loading on the Stress Response of Physician

This study is currently recruiting participants.
Verified January 2012 by National Taiwan University Hospital
Sponsor:
Collaborator:
Taipei City Hospital
Information provided by (Responsible Party):
National Taiwan University Hospital
ClinicalTrials.gov Identifier:
NCT01367379
First received: June 3, 2011
Last updated: January 3, 2012
Last verified: January 2012
History of Changes
  Purpose

The investigators will study in the possibility of cardiovascular disease, caused by the duty loading, of physician of internal medicine. The investigators will also explore if there {dose response effect} between the duty loading and the stress response of physicians of internal medicine. Therefore, the investigators will compare the stress responses of physicians of internal medicine during with different duty loading ( non-duty day, one duty area with 3 wards, 2 duty areas with 6 wards) in a observational method. Those stress response will be measured by cardiovascular risk indicators, including blood pressure, heart rate variability, blood sampling and urine sampling.


Condition Intervention
Physiological Stress
Psychological Stress
 Procedure: 24 hour EKG and blood pressure monitor
Other: Blood and urine sampling

Study Type: Observational
Study Design: Observational Model: Case-Crossover
Time Perspective: Prospective
Official Title: The Effect of the Duty Loading on the Stress Response of Physician

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by National Taiwan University Hospital:

Primary Outcome Measures:
  • The physiological change of physician during different duty loadings [ Time Frame: 4 months ] [ Designated as safety issue: No ]
    The investigators will also explore if there {dose response effect} between the duty loading and the stress response of physicians of internal medicine, and will compare the stress responses of physicians of internal medicine during with different duty loading in a observational method. Those stress response will be measured by cardiovascular risk indicators, including blood pressure, heart rate variability, blood sampling and urine sampling.


Estimated Enrollment: 15
Study Start Date: June 2011
Estimated Study Completion Date: December 2012
Estimated Primary Completion Date: December 2012 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Physician of internal medicine in Taipei city hospital Procedure: 24 hour EKG and blood pressure monitor
All subjects will have non-invasive 24 hour EKG and 24 hour EKG monitoring for 24 hours.
Other: Blood and urine sampling
Right before and after the duty loading, all subjects will have blood samplings, including CRP, WBC, IL-6, Fibrinogen, insulin, IL-6, Procalcitonin, TNF-alfa, catecholamine level. Right after the duty loading, all subjects will have urine samplings for cortisol and catecholamine level.(blood : 15CC/time and 2~4 times/month)

  Eligibility

Ages Eligible for Study:   30 Years to 60 Years
Genders Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population

Attending physicians of internal medicine of Taipei municipal hospital, certified by Taiwan society of internal medicine. We will compare those results of outcome variables of different amount of duty area.

Criteria

Inclusion Criteria:

  • Attending physicians of internal medicine of Taipei municipal hospital, certified by Taiwan society of internal medicine.

Exclusion Criteria:

  • thyroid dysfunction
  • pregnancy, diabetes mellitus
  • history of cardiovascular disease (stroke, coronary arterial disease, or myocardial infraction)
  • current smokers, or
  • taking sleeping pills or B-blocker
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01367379

Contacts
Contact: Hsiu Hao Lee, MD 886-2-25523234 ext 5540 limax0809@gmail.com

Locations
Taiwan
National Taiwan university hospital Recruiting
Taipei, Taiwan, 100
Contact: Hsiu Hao Lee, MD     886-25523234 ext 5540     limax0809@gmail.com    
Sponsors and Collaborators
National Taiwan University Hospital
Taipei City Hospital
Investigators
Principal Investigator: Yue Leon Guo, Professor National Taiwan University Hospital
  More Information

No publications provided

Responsible Party: National Taiwan University Hospital
ClinicalTrials.gov Identifier: NCT01367379     History of Changes
Other Study ID Numbers: 201104059RC
Study First Received: June 3, 2011
Last Updated: January 3, 2012
Health Authority: Taiwan: Department of Health

Keywords provided by National Taiwan University Hospital:
Physician
duty loading
stress response
Physician with different amount of duty area

Additional relevant MeSH terms:
Stress, Psychological
Behavioral Symptoms

ClinicalTrials.gov processed this record on June 18, 2013