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Clinical Study of Novel Diagnostic Techniques for Knee Osteoarthritis

The recruitment status of this study is unknown because the information has not been verified recently.
Verified May 2011 by University of Oulu.
Recruitment status was  Recruiting
Sponsor:
Collaborators:
Oulu University Hospital
University of Eastern Finland
Kuopio University Hospital
Information provided by:
University of Oulu
ClinicalTrials.gov Identifier:
NCT01359553
First received: May 22, 2011
Last updated: NA
Last verified: May 2011
History: No changes posted
  Purpose

The purpose of this study is to clarify the potential of intra-articular ultrasound imaging, non-invasive ultrasound imaging, quantitative MRI imaging, contrast-enhanced CT imaging and arthroscopy for diagnostics of knee osteoarthritis. All methods will be cross-correlated and compared with the arthroscopic findings.


Condition Intervention
Knee Osteoarthritis
Knee Injuries
 Other: Intra-articular ultrasound imaging of knee joint during arthroscopy
Other: Non-invasive ultrasound imaging of knee
Other: Quantitative MRI imaging of knee
Other: Contrast-enhanced CT imaging of knee

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Cross-Sectional
Official Title: Comparison Between Intra-articular Ultrasound Imaging, Non-invasive Ultrasound Imaging, Quantitative MRI Imaging, Contrast-enhanced CT Imaging and Arthroscopy for Diagnostics of Knee Osteoarthritis

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by University of Oulu:

Estimated Enrollment: 30
Study Start Date: May 2011
Groups/Cohorts Assigned Interventions
Knee pain
Group with knee pain problems referred to an arthroscopy.
 Other: Intra-articular ultrasound imaging of knee joint during arthroscopy Other: Non-invasive ultrasound imaging of knee Other: Quantitative MRI imaging of knee Other: Contrast-enhanced CT imaging of knee

  Eligibility

Ages Eligible for Study:   20 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Patients will be selected from those referred to an arthroscopy because of pain symptoms in the knee.

Criteria

Inclusion Criteria:

  • Kellgren-Lawrence grade = 1-3 or cartilage defect detected in MRI
  • Age >= 20 years

Exclusion Criteria:

  • Tumor or inflammation in the knee
  • Severe general diseases
  • Diabetes
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01359553

Contacts
Contact: Esa Liukkonen, Ph.D. esa.liukkonen@ppshp.fi

Locations
Finland
Oulu University Hospital Recruiting
Oulu, Finland, FI-90029
Contact: Simo Saarakkala, Ph.D.         simo.saarakkala@oulu.fi    
Principal Investigator: Simo Saarakkala, Ph.D.            
Sub-Investigator: Petri Lehenkari, M.D., Ph.D.            
Sub-Investigator: Miika T Nieminen, Ph.D.            
Sub-Investigator: Risto Ojala, M.D., Ph.D.            
Sponsors and Collaborators
University of Oulu
Oulu University Hospital
University of Eastern Finland
Kuopio University Hospital
Investigators
Principal Investigator: Simo Saarakkala, Ph.D. University of Oulu and Oulu University Hospital
Study Director: Petri Lehenkari, M.D., Ph.D. University of Oulu and Oulu University Hospital
Study Director: Miika T Nieminen, Ph.D. University of Oulu and Oulu University Hospital
Study Director: Risto Ojala, M.D., Ph.D. Oulu University Hospital
  More Information

No publications provided

Responsible Party: Simo Saarakkala, Ph.D., Department of Diagnostic Radiology, Oulu University Hospital
ClinicalTrials.gov Identifier: NCT01359553     History of Changes
Other Study ID Numbers: UltraRusto
Study First Received: May 22, 2011
Last Updated: May 22, 2011
Health Authority: Finland: Ministry of Social Affairs and Health

Additional relevant MeSH terms:
Knee Injuries
Osteoarthritis
Osteoarthritis, Knee
Leg Injuries
Wounds and Injuries
 Arthritis
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases

ClinicalTrials.gov processed this record on June 17, 2013