REVOLUTION (WFCC-133)

Inclusion Criteria:

1. Patients with symptomatic PAF who have had at least one documented AF episode in the twelve (12) months prior to enrollment. Documentation may include ECG, transtelephonic monitor (TTM), Holter Monitor (HM), or telemetry strip.
2. Failure of at least one antiarrhythmic drug for AF (class I or III, or AV nodal blocking agents such as beta blockers and calcium channel blockers), as evidenced by recurrent symptomatic AF, or intolerable side effects.
3. Age 18 years or older.
4. Able and willing to comply with all pre-, post- and follow-up testing and requirements.
5. Signed Patient Informed Consent Form.

Exclusion Criteria:

1. AF secondary to electrolyte imbalance, thyroid disease, or reversible or non-cardiac cause.
2. Patients with Persistent or Long-standing AF (AF episode lasting > 30 days in duration.
3. Diagnosed atrial myxoma.
4. Left atrial size > 5.5cm.
5. Left Ventricular ejection fraction < 40%.
6. Contraindication to CT/MRI procedures
7. New York Heart Association Class III or IV.
8. Previous ablation for enrolled arrhythmia (AF).
9. Documented left atrial thrombus on imaging (eg transesophageal echocardiography or intracardiac echocardiography).
10. Myocardial Infarction within the previous 60 days (2 months).
11. Any valvular cardiac surgical procedure (ie, valve repair or replacement and presence of a prosthetic valve).
12. Coronary artery bypass graft procedure with the last 180 days 6 months.
13. Cardiac Surgery (i.e. ventriculotomy, atriotomy) within the past 60 days (2 months).
14. Awaiting cardiac transplantation or other cardiac surgery within the next 365 days (12 months).
15. History of documented thromboembolic event within the past one (1) year.
16. Significant pulmonary disease, (eg restrictive pulmonary disease, constrictive or chronic obstructive pulmonary disease) or any other disease or malfunctions of the lungs or respiratory system that produces chronic symptoms.
17. Significant congenital anomaly or medical problem that in the opinion of the investigator would preclude enrollment in this study.
18. Active illness or active systemic infection or sepsis.
19. Unstable angina.
20. History of blood clotting or bleeding abnormalities.
21. Contraindication to anticoagulation (ie Heparin or Warfarin).
22. Life expectancy less than 365 days (12 months)
23. Presence of intramural thrombus, tumor or other abnormality that precludes catheter introduction or manipulation.
24. Women who are pregnant (as evidence by pregnancy test if subject is of child bearing potential) and/or breast feeding.
25. Presence of a condition that precludes vascular access.
26. Enrollment in an investigational study evaluating another device or drug.