Trial record 10 of 12 for:    LRRK2

Web-based Genetic Research on Parkinson's Disease

This study is currently recruiting participants.
Verified May 2011 by 23andMe, Inc.
Sponsor:
Collaborators:
Michael J. Fox Foundation for Parkinson's Research
The Parkinson's Institute
Information provided by:
23andMe, Inc.
ClinicalTrials.gov Identifier:
NCT01351467
First received: May 9, 2011
Last updated: May 10, 2011
Last verified: May 2011
  Purpose

The purpose of this study is to examine how genes and environment affect risk for Parkinson's disease.


Condition
Parkinson's Disease

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: Ongoing, Web-Based Genome-Wide Association Studies

Resource links provided by NLM:


Further study details as provided by 23andMe, Inc.:

Biospecimen Retention:   Samples With DNA

Saliva samples are collected for DNA analysis


Estimated Enrollment: 10000
Study Start Date: April 2009
Estimated Study Completion Date: January 2020
Estimated Primary Completion Date: January 2015 (Final data collection date for primary outcome measure)
Groups/Cohorts
Parkinson's disease patients
People diagnosed with Parkinson's disease by a physician

Detailed Description:

23andMe has created a web-based Parkinson's Research Community to examine how genes and environment are related to risk for Parkinson's. Conducting the study online can significantly accelerate the pace of this research, which seeks to enroll 10,000 people with Parkinson's. The online study design allows people diagnosed with Parkinson's to participate from any location (www.23andme.com/pd). It's free to participate, and anyone that has been diagnosed with Parkinson's by a physician is eligible. Enrollment is on-going and participants can sign up at any time. Participants provide a saliva sample for DNA testing and fill out surveys online about their symptoms, experiences and environmental exposures. 23andMe uses this information to conduct Genome Wide Association Studies to find genes that are significantly correlated with Parkinson's. In return, participants can see their own genetic information, including whether they carry certain mutations associated with Parkinson's, but they can also choose not to view their results. 23andMe provides materials and support to explain what the results mean, through online tutorials, videos and the patient liaison (pd-help@23andme.com). Additionally, participants are kept informed of research discoveries made in the project and how this relates to them. To sign up, visit www.23andme.com/pd

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Community Sample

Criteria

Inclusion Criteria:

  • diagnosis of Parkinson's disease by a physician

Exclusion Criteria:

  • diagnoses other than Parkinson's, including:
  • progressive supranuclear palsy (PSP)
  • multiple system atrophy (MSA)
  • Shy-Drager syndrome
  • spinal cerebella ataxia (SCA)
  • atypical parkinsonism
  • parkinsonism due to medications, drug-induced parkinsonism
  • vascular parkinsonism
  • frontotemporal dementia with parkinsonism
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01351467

Contacts
Contact: Emily M Drabant, Ph.D. 6509386300 pd-help@23andme.com

Locations
United States, California
Www.23Andme.Com/Pd Recruiting
Mountain View, California, United States, 94043
Contact: Emily M Drabant, Ph.D.    650-938-6300    pd-help@23andme.com   
Sponsors and Collaborators
23andMe, Inc.
Michael J. Fox Foundation for Parkinson's Research
The Parkinson's Institute
  More Information

Additional Information:
No publications provided

Responsible Party: Dr. Joanna Mountain, Senior Director of Research, 23andMe
ClinicalTrials.gov Identifier: NCT01351467     History of Changes
Other Study ID Numbers: 23andMe_PD001
Study First Received: May 9, 2011
Last Updated: May 10, 2011
Health Authority: United States: Institutional Review Board

Keywords provided by 23andMe, Inc.:
Parkinson's
genetic
online
GWAS
genome wide association
LRRK2

Additional relevant MeSH terms:
Parkinson Disease
Parkinsonian Disorders
Basal Ganglia Diseases
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Movement Disorders
Neurodegenerative Diseases

ClinicalTrials.gov processed this record on April 22, 2014