Web-based Genetic Research on Parkinson's Disease
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Purpose
The purpose of this study is to examine how genes and environment affect risk for Parkinson's disease.
| Condition |
|---|
|
Parkinson's Disease |
| Study Type: | Observational |
| Study Design: | Observational Model: Case Control Time Perspective: Cross-Sectional |
| Official Title: | Ongoing, Web-Based Genome-Wide Association Studies |
Saliva samples are collected for DNA analysis
| Estimated Enrollment: | 10000 |
| Study Start Date: | April 2009 |
| Estimated Study Completion Date: | January 2020 |
| Estimated Primary Completion Date: | January 2015 (Final data collection date for primary outcome measure) |
| Groups/Cohorts |
|---|
|
Parkinson's disease patients
People diagnosed with Parkinson's disease by a physician
|
Detailed Description:
23andMe has created a web-based Parkinson's Research Community to examine how genes and environment are related to risk for Parkinson's. Conducting the study online can significantly accelerate the pace of this research, which seeks to enroll 10,000 people with Parkinson's. The online study design allows people diagnosed with Parkinson's to participate from any location (www.23andme.com/pd). It's free to participate, and anyone that has been diagnosed with Parkinson's by a physician is eligible. Enrollment is on-going and participants can sign up at any time. Participants provide a saliva sample for DNA testing and fill out surveys online about their symptoms, experiences and environmental exposures. 23andMe uses this information to conduct Genome Wide Association Studies to find genes that are significantly correlated with Parkinson's. In return, participants can see their own genetic information, including whether they carry certain mutations associated with Parkinson's, but they can also choose not to view their results. 23andMe provides materials and support to explain what the results mean, through online tutorials, videos and the patient liaison (pd-help@23andme.com). Additionally, participants are kept informed of research discoveries made in the project and how this relates to them. To sign up, visit www.23andme.com/pd
Eligibility| Ages Eligible for Study: | 18 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Community Sample
Inclusion Criteria:
- diagnosis of Parkinson's disease by a physician
Exclusion Criteria:
- diagnoses other than Parkinson's, including:
- progressive supranuclear palsy (PSP)
- multiple system atrophy (MSA)
- Shy-Drager syndrome
- spinal cerebella ataxia (SCA)
- atypical parkinsonism
- parkinsonism due to medications, drug-induced parkinsonism
- vascular parkinsonism
- frontotemporal dementia with parkinsonism
Contacts and Locations| Contact: Emily M Drabant, Ph.D. | 6509386300 | pd-help@23andme.com |
| United States, California | |
| Www.23Andme.Com/Pd | Recruiting |
| Mountain View, California, United States, 94043 | |
| Contact: Emily M Drabant, Ph.D. 650-938-6300 pd-help@23andme.com | |
More Information
Additional Information:
No publications provided
| Responsible Party: | Dr. Joanna Mountain, Senior Director of Research, 23andMe |
| ClinicalTrials.gov Identifier: | NCT01351467 History of Changes |
| Other Study ID Numbers: | 23andMe_PD001 |
| Study First Received: | May 9, 2011 |
| Last Updated: | May 10, 2011 |
| Health Authority: | United States: Institutional Review Board |
Keywords provided by 23andMe, Inc.:
|
Parkinson's genetic online |
GWAS genome wide association LRRK2 |
Additional relevant MeSH terms:
|
Parkinson Disease Parkinsonian Disorders Basal Ganglia Diseases Brain Diseases |
Central Nervous System Diseases Nervous System Diseases Movement Disorders Neurodegenerative Diseases |
ClinicalTrials.gov processed this record on June 18, 2013