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Effects of Massage Versus Rest on Hormones

This study has been completed.
Sponsor:
Collaborator:
Gruter Institute
Information provided by:
Claremont Graduate University
ClinicalTrials.gov Identifier:
NCT01351402
First received: May 6, 2011
Last updated: May 9, 2011
Last verified: August 2005
History of Changes
  Purpose

This study will investigate the effects of 15 minutes of massage compared to 15 minutes of quiet rest on physiological variables. Specifically, the investigators will measure the effects on levels of the social hormone oxytocin, and on other physiological variables that interact with oxytocin or that may be influenced by massage (including ACTH, Beta-endorphin, and IL-1alpha). The investigators will also investigate whether, in the case of hormones changes, these influence social decision making.


Condition Intervention
Massage
Rest
 Procedure: Massage or Rest

Study Type: Interventional
Study Design: Allocation: Randomized
Masking: Single Blind
Primary Purpose: Basic Science
Official Title: Investigating the Effects of Massage vs. Rest on Oxytocin, ACTH, and B-endorphins

Further study details as provided by Claremont Graduate University:

Primary Outcome Measures:
  • Oxytocin [ Time Frame: Within 5 minutes following experimental manipulation of either 15 minutes massage or rest. ] [ Designated as safety issue: No ]
    Participants receive a blood draw at baseline and immediately following 15 minutes of massage or rest and oxytocin will be measured from this sample.


Secondary Outcome Measures:
  • Adrenocorticotrophic hormone (ACTH) [ Time Frame: Within 5 minutes following experimental manipulation of either 15 minutes massage or rest. ]
    Participants will receive a blood draw at baseline and immediately following 15 minutes of massage or rest, and ACTH will be measured in these blood samples.

  • Beta-endorphin [ Time Frame: Within 5 minutes following experimental manipulation of either 15 minutes massage or rest. ]
    Participants will receive a blood draw at baseline and immediately following 15 minutes of massage or rest, and B-endorphin will be measured from these samples.

  • Interleukin-1alpha (IL-1a) [ Time Frame: Within 5 minutes following experimental manipulation of either 15 minutes massage or rest. ]
    Participants will receive a blood draw at baseline and immediately following 15 minutes of massage or rest, and IL-1a will be measured from these samples.


Enrollment: 95
Study Start Date: June 2006
Study Completion Date: January 2007
Primary Completion Date: August 2006 (Final data collection date for primary outcome measure)
Intervention Details:
    Procedure: Massage or Rest
    Participants either received 15 minutes of moderate pressure Swedish massage on the upper back, or rested quietly sitting in a chair for 15 minutes.
Detailed Description:

Interested participants will have the experiment explained both verbally and in writing, and asked to give their informed consent in writing. After consent, the participants will be led to a private room for their first 30ml blood draw by a qualified phlebotomist. Participants will then have a second 30ml blood draw.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Anyone English speaking and over the age of 18.

Exclusion Criteria:

  • Minors and anyone who has used illicit drugs or alcohol in the last 24 hours.
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01351402

Locations
United States, California
Cassel, UCLA
Los Angeles, California, United States, 90095
Sponsors and Collaborators
Claremont Graduate University
Gruter Institute
  More Information

No publications provided

Responsible Party: Paul J. Zak, Ph.D., Center for Neuroeconomic Studies, Claremont Graduate University
ClinicalTrials.gov Identifier: NCT01351402     History of Changes
Other Study ID Numbers: 00012002
Study First Received: May 6, 2011
Last Updated: May 9, 2011
Health Authority: United States: Institutional Review Board

Keywords provided by Claremont Graduate University:
Massage
Rest

ClinicalTrials.gov processed this record on May 19, 2013