Efficacy of Alcohol Hand-rubbing Covering All Hand Surfaces in Reducing Bacterial Hand Contamination of Healthcare Staff (B/07/310)

This study has been completed.
Sponsor:
Information provided by:
Tan Tock Seng Hospital
ClinicalTrials.gov Identifier:
NCT01337856
First received: April 13, 2011
Last updated: April 18, 2011
Last verified: April 2011
  Purpose

This is a randomized controlled trial comparing the effectiveness of three hand hygiene protocols, during routine inpatient clinical care: Protocol 1: handrubbing with alcohol covering all hand surfaces in no particular order; Protocol 2: handrubbing with alcohol using the WHO standard 7-step technique; and Protocol 3: handwashing with chlorhexidine using the WHO standard 7-step technique.

The main study hypothesis is that alcohol hand-rubbing covering all hand surfaces is not less effective in reducing bacterial hand contamination of healthcare staff than alcohol hand-rubbing using 7-step technique; and is more effective than chlorhexidine handwashing. The secondary study hypothesis is that time spent on alcohol hand-rubbing covering all hand surfaces is less than that required by the other 2 hand hygiene protocols respectively.


Condition Intervention
Efficacy of Hand Hygiene Protocols
Other: Hand hygiene protocol

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Health Services Research
Official Title: Efficacy of Alcohol Hand-rubbing Covering All Hand Surfaces in Reducing Bacterial Hand Contamination of Healthcare Staff

Resource links provided by NLM:


Further study details as provided by Tan Tock Seng Hospital:

Primary Outcome Measures:
  • reduction of hand bacterial load [ Time Frame: hand samples will be analyzed up to 11 months after collection; data will be presented for an average of 5 years after data collection ] [ Designated as safety issue: No ]
    The primary outcome measure of the study was to ascertain the effectiveness of the three hand-hygiene protocols, in the reduction of hand bacterial load. Quantitative reduction in bacterial load will be measured in colony forming units per mililiter (cfu/ml). Bacteria will be qualitatively identified, and sensitivity to antibiotics determined.


Secondary Outcome Measures:
  • time spent on hand hygiene [ Time Frame: participants will be observed for the duration of hand hygiene; data will be presented for an average of 5 years after data collection ] [ Designated as safety issue: No ]
    The secondary outcome measure include the estimation of time spent on hand hygiene, for each hand hygiene protocol. Time will be measured in seconds.


Enrollment: 120
Study Start Date: October 2007
Study Completion Date: September 2008
Primary Completion Date: September 2008 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
WHO alcohol handrub protocol
handrubbing with alcohol using the standard 7-step technique (WHO alcohol handrub protocol)
Other: Hand hygiene protocol
Comparison of efficacy of 3 hand hygiene protocols
Other Names:
  • time-effectiveness
  • efficacy
  • hand hygiene
  • alcohol handrub
CDC alcohol handrub protocol
Handrubbing with alcohol covering all hand surfaces in no particular order (CDC alcohol handrub protocol)
Other: Hand hygiene protocol
Comparison of efficacy of 3 hand hygiene protocols
Other Names:
  • time-effectiveness
  • efficacy
  • hand hygiene
  • alcohol handrub
Chlorhexidine handwashing
chlorhexidine handwashing using the standard 7-step technique (WHO handwashing protocol)
Other: Hand hygiene protocol
Comparison of efficacy of 3 hand hygiene protocols
Other Names:
  • time-effectiveness
  • efficacy
  • hand hygiene
  • alcohol handrub

  Show Detailed Description

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

medical and nursing staff working in general wards in Tan Tock Seng Hospital

  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01337856

Locations
Singapore
Tan Tock Seng Hospital
Singapore, Singapore, 308433
Sponsors and Collaborators
Tan Tock Seng Hospital
Investigators
Principal Investigator: Angela LP Chow, MBBS, MPH Tan Tock Seng Hospital
  More Information

No publications provided

Responsible Party: Angela Chow, Tan Tock Seng Hospital
ClinicalTrials.gov Identifier: NCT01337856     History of Changes
Other Study ID Numbers: NHG DSRB B/07/310, SIG08012
Study First Received: April 13, 2011
Last Updated: April 18, 2011
Health Authority: Singapore: Health Sciences Authority

Keywords provided by Tan Tock Seng Hospital:
time-effectiveness
hand hygiene protocols

Additional relevant MeSH terms:
Ethanol
Chlorhexidine
Anti-Infective Agents, Local
Anti-Infective Agents
Therapeutic Uses
Pharmacologic Actions
Central Nervous System Depressants
Physiological Effects of Drugs
Central Nervous System Agents
Disinfectants

ClinicalTrials.gov processed this record on April 22, 2014