Monitoring the Response of Port Wine Stain Birthmarks to Laser Therapy With Wide-field Functional Imaging Technologies
The researcher at the Beckman Laser Institute develop non-invasive imaging modalities for assessment of port wine stain (PWS) during laser therapy treatment. The imaging modalities will be used to guide immediate retreatment of regions of persistent perfusion during the procedure.
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||Monitoring the Response of PWS Birthmarks to Laser Therapy With Wide-field|
- Method to monitor the response of laser treatment of port wien stain [ Time Frame: 1 week ] [ Designated as safety issue: No ]The proposed research is significant, because our image-guided surgery approach will show color images which will be used to adjust energy of the laser treatment, reducing ultimately the number of treatment sessions and the associated medical care burden.
|Study Start Date:||April 2010|
|Estimated Study Completion Date:||June 2017|
|Estimated Primary Completion Date:||June 2017 (Final data collection date for primary outcome measure)|
Laser Speckle Imaging
Laser Speckle Imaging
Device: Laser Speckle Imaging
Assessment of port wine stain birthmarks to laser therapy
The degree of photocoagulation caused by laser therapy will be assessed with LSI and SFDI.The imaging system operates by projecting low-power near-infrared structured light patterns on to the tissue of interest in a non-contact, reflection geometry and then capturing the reflectance with a CCD camera.The system can image the depth-resolved optical properties of in-vivo tissues, allowing rapid, non-invasive 3D visualization of sub-surface structures.
|Contact: Montana Compton, RNemail@example.com|
|United States, California|
|Beckman Laser Institute Medical clinic||Recruiting|
|Irvine, California, United States, 92612|
|Contact: Montana Compton, RN 949-824-9265 firstname.lastname@example.org|
|Sub-Investigator: Stuart Nelson, MD,PhD|
|Sub-Investigator: Kristen Kelly, MD|
|Principal Investigator:||Bernard Choi, PhD||Beckman Laser Institute University of California Irvine|