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Anesthetic Efficacy of Gow-Gates Versus Conventional Inferior Alveolar Nerve Block Techniques

The recruitment status of this study is unknown because the information has not been verified recently.
Verified January 2011 by Mashhad University of Medical Sciences.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Mashhad University of Medical Sciences
ClinicalTrials.gov Identifier:
NCT01329874
First received: April 4, 2011
Last updated: April 5, 2011
Last verified: January 2011
  Purpose

The purpose of this study is to determine whether Gow Gates block injection is more effective than conventional alveolar nerve block in anesthetising mandibular molars with acute pulpitis.


Condition Intervention
Anesthesia; Reaction
Pain
Procedure: Type of block injection

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
Official Title: Comparison of the Anesthetic Efficacy in Mandibular Molars With Acute Irreversible Pulpitis With Either Conventional Inferior Alveolar or Gow-gates Nerve Block Techniques Plus Buccal or Lingual Infiltration

Further study details as provided by Mashhad University of Medical Sciences:

Primary Outcome Measures:
  • Number of participant who will have pain following Gow gates or traditional inferior alveolar nerve block [ Time Frame: 6 months ] [ Designated as safety issue: No ]
    All participant asked to show their pain degree on VAS for evaluation the efficacy of two different block injections and two different infiltrations ( Buccal and lingual) as supplementary injections.


Secondary Outcome Measures:
  • Heart rate monitoring [ Time Frame: before and after block injections (day 1) ] [ Designated as safety issue: No ]
    These records will be monitored by pulse oximeter device


Estimated Enrollment: 80
Study Start Date: March 2011
Estimated Study Completion Date: September 2011
Estimated Primary Completion Date: June 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
No Intervention: Gow gates ,conventional block injection
Patients will be selected from a group with acute irreversible pulpitis in mandibular molars. Half of the patients randomly selected for receiving gow gates block injection and half will receive traditional inferior block injection by 3.6 ml Lidocaine plus epinephrine.Teeth with no response to anesthetizing will be randomly divided into two group of either buccal or lingual infiltration.
Procedure: Type of block injection
Patients will be selected from a group with acute irreversible pulpitis in mandibular molars. Half of the patients randomly selected for receiving gow gates block injection and half will receive traditional inferior block injection by 3.6 ml Lidocaine plus epinephrine.Teeth with no response to anesthetizing will be randomly divided into two group of either buccal or lingual infiltration.
Other Names:
  • Gow Gates technique
  • Conventional inferior block injection
No Intervention: Buccal infiltration, Lingual infiltration

Detailed Description:

Pain management and adequate anesthesia are of critical importance for the endodontist. Traditionally, mandibular teeth are anesthetized via inferior alveolar nerve block (IAN). However, this technique provides a marginal success rate of 19-56% in patients with irreversible pulpitis.Gow Gates technique introduced in 1973 for anesthetizing of mandibular molars with more accuracy, success and safety.

  Eligibility

Ages Eligible for Study:   12 Years to 50 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Mandibular molars with acute irreversible pulpitis

Exclusion Criteria:

  • Unhealthy patients
  • Patients who had taken pain killer less than 4 hours before appointment
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01329874

Contacts
Contact: Mohammad Hasan Zarrabi, D.D.S,M.S.c +985118829525 ext 291 zarrabimh@mums.ac.ir
Contact: Farzaneh Daneshvar, D.D.S +985118829525 ext 165 daneshvarf@mums.ac.ir

Locations
Iran, Islamic Republic of
Dept of Endodontics, Faculty of Dentistry Recruiting
Mashhad, Khorasan Razavi, Iran, Islamic Republic of, 91735
Contact: Mohammad Hasan Zarrabi, D.D.S,M.S.c    +985118829525 ext 291    zarrabimh@mums.ac.ir   
Contact: Farzaneh Daneshvar, D.D.S    +985118829525 ext 165    daneshvarf@mums.ac.ir   
Sub-Investigator: Mohammad Hasan Zarrabi, D.D.S,M.S.c         
Sponsors and Collaborators
Mashhad University of Medical Sciences
Investigators
Principal Investigator: Jamileh Ghoddusi, D.D.S,M.S.c Dental Research Center, Faculty of Dentistry, Mashhad University of Medical Sciences
  More Information

No publications provided

Responsible Party: Research Manager of Mashhad University of Medical Sciences, Mashhad University of Medical Sciences
ClinicalTrials.gov Identifier: NCT01329874     History of Changes
Other Study ID Numbers: 89549
Study First Received: April 4, 2011
Last Updated: April 5, 2011
Health Authority: Iran: Ministry of Health

Additional relevant MeSH terms:
Anesthetics
Central Nervous System Agents
Central Nervous System Depressants
Pharmacologic Actions
Physiological Effects of Drugs
Therapeutic Uses

ClinicalTrials.gov processed this record on November 25, 2014