A Study of Vitamin D in Subjects With Alopecia Areata
The objective of this study is to assess the parathyroid-vitamin D-calcium axis in subjects with alopecia areata. The hypothesis behind this study is that hypovitaminosis D might contribute to the pathogenesis of alopecia areata.
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||A Pilot Study of Vitamin D in Subjects With Alopecia Areata|
- Vitamin D levels will be reported in subjects and correlated with the calcium and parathyroid levels. [ Time Frame: Initial clinic visit (day 1) ] [ Designated as safety issue: No ]This study consists of a single clinic visit. After subject has completed the informed consent process and meets eligibility criteria, a blood sample will be collected. Lab results from this one-time lab draw will be evaluated.
Biospecimen Retention: Samples Without DNA
|Study Start Date:||August 2009|
|Study Completion Date:||July 2011|
|Primary Completion Date:||July 2011 (Final data collection date for primary outcome measure)|
Individuals with Alopecia Areata (AA)
Alopecia Areata (AA) is a T-Cell mediated, non-scarring, polygenic, autoimmune disease of the hair follicle. It has been reported to be associated with other autoimmune diseases, especially autoimmune thyroid disease and vitiligo. It is more common in females. Recently, vitamin D deficiency has been claimed to contribute to the pathogenesis of multiple autoimmune disease. There is a strong inverse correlation between the level of 25-hydroxyvitamin D levels and the autoimmune disease in adolescents.
|United States, South Dakota|
|Avera Research Institute|
|Sioux Falls, South Dakota, United States, 57105|
|Principal Investigator:||Wael Eid, MD||Avera McKennan Hospital & University Health Center|