Study Of The Long Term Outcome Of Tuberculous Meningitis In Vietnamese Adults Treated With Adjunctive Dexamethasone (ES)
All patients who were alive at the end of the dexamethasone treatment trial conducted by Oxford University CLinical Research Unit from 2001-2005 (n=340) will be eligible to participate in this long-term follow-up study.
All eligible and consenting patients will undergo an assesment consisting of a simple questionnaire, a clinical examination and a blood test. Data collected will focus on survival, neurological disability and tuberculosis relapse. Data will be collected in individual case record forms and entered into a computer database.
|Study Design:||Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:||Study Of The Long Term Outcome Of Tuberculous Meningitis In Vietnamese Adults Treated With Adjunctive Dexamethasone|
- Survival [ Time Frame: 5 years ] [ Designated as safety issue: No ]
- Neurological disability [ Time Frame: 5 years ] [ Designated as safety issue: No ]
- Tuberculosis relapse rate [ Time Frame: 5 years ] [ Designated as safety issue: No ]
|Study Start Date:||April 2006|
|Study Completion Date:||April 2008|
|Primary Completion Date:||April 2008 (Final data collection date for primary outcome measure)|
|Survivors of TBM trial 2001-2005||
Collection of mortality data at 5 years post trial
Please refer to this study by its ClinicalTrials.gov identifier: NCT01317654
|Principal Investigator:||Estee Torok, MD||Oxford University Clinical Research Unit - Viet Nam|