Now Available for Public Comment: Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials

Feeling of Being in Control of One's Own Action

This study is currently recruiting participants. (see Contacts and Locations)
Verified June 2014 by University Hospital, Strasbourg, France
Information provided by (Responsible Party):
University Hospital, Strasbourg, France Identifier:
First received: March 1, 2011
Last updated: June 26, 2014
Last verified: June 2014

The investigators aim is to understand the cognitive mechanisms that contribute to the emergence of delusions of control (the belief that one's own actions or thoughts are controlled by an external force). These symptoms are mainly encountered in patients with schizophrenia, and the investigators will distinguish patients with schizophrenia with or without this symptom together with patients with bipolar disorder. Based on the investigators previous studies, this project will help to determine the role of two elementary mechanisms in the ability to feel in control of voluntary actions: (1) the processing of the sensory consequences of action, and (2) the ability to build mental representations for sequenced actions.

Condition Intervention
Bipolar Disorders
Behavioral: Experimental psychology methods (computer tests)

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Basic Science
Official Title: Feeling of Being in Control of One's Own Action: Which Mechanisms in Healthy Volunteers and in Mental Diseases

Resource links provided by NLM:

Further study details as provided by University Hospital, Strasbourg, France:

Estimated Enrollment: 370
Study Start Date: April 2011
Estimated Study Completion Date: October 2015
Estimated Primary Completion Date: October 2015 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Arm 1
Healthy volunteers
Behavioral: Experimental psychology methods (computer tests)
Experimental: Arm 2
Schizophrenia with history of delusions of control
Behavioral: Experimental psychology methods (computer tests)
Experimental: Arm 3
Schizophrenia without history of delusions of control
Behavioral: Experimental psychology methods (computer tests)
Experimental: Arm 4
Bipolar disorders
Behavioral: Experimental psychology methods (computer tests)
Active Comparator: Arm 5
Matched healthy controls
Behavioral: Experimental psychology methods (computer tests)


Ages Eligible for Study:   18 Years to 55 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Patients with schizophrenia or bipolar disorders (criteria DSM IV) or healthy controls matched with patients on age, sex and education level
  • 18-55 years old

Exclusion Criteria:

  • Past history affecting CNS
  • Invalidating sensory disorders
  • Intake of psychotropic drugs, except for patients
  • Intake of benzodiazepines
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01312649

Contact: Anne Giersch

Pôle de Psychiatrie - Hôpital civil Recruiting
Strasbourg, France
Contact: Anne GIERSCH, MD   
Sub-Investigator: Gilles BERTSCHY, MD         
Sub-Investigator: Laurence LALANNE, MD         
Sub-Investigator: Sebastien WEIBEL, MD         
Principal Investigator: Anne GIERSCH, MD         
Sponsors and Collaborators
University Hospital, Strasbourg, France
Study Director: Anne GIERSCH, MD Hôpitaux Universitaires de Strasbourg
  More Information

No publications provided

Responsible Party: University Hospital, Strasbourg, France Identifier: NCT01312649     History of Changes
Other Study ID Numbers: 4880
Study First Received: March 1, 2011
Last Updated: June 26, 2014
Health Authority: France: Ministry of Health

Additional relevant MeSH terms:
Bipolar Disorder
Affective Disorders, Psychotic
Mental Disorders
Mood Disorders
Schizophrenia and Disorders with Psychotic Features processed this record on November 20, 2014