Evaluation of Graft Material in Coronary Artery Bypass Grafting (CABG)
The aim of the study is to evaluate the patency in different kinds of vessels used as graft material in coronary artery bypass grafting.
The hypothesis is that vein grafts harvested with a pedicle of surrounding tissue have the same, or better, patency compared to radial grafts and that skeletonisation of the left internal mammary artery does not effect the patency for this graft.
|Study Design:||Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Single Group Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:||Mid-term Patency of Radial Artery and No Touch Saphenous Vein as Grafts in CABG; A Randomised Controlled Trial.|
- Functional grafts defined as opened or closed. [ Time Frame: Up to 5 years after surgery. ] [ Designated as safety issue: Yes ]
- Degree of stenosis in implanted grafts. [ Time Frame: Up to 5 years after surgery. ] [ Designated as safety issue: Yes ]
|Study Start Date:||January 2004|
|Study Completion Date:||November 2010|
|Primary Completion Date:||November 2010 (Final data collection date for primary outcome measure)|
Procedure: Coronary artery bypass grafting
Patients undergoing coronary artery bypass grafting are included in the study.
Each patient receive a radial artery graft and a vein graft harvested with a pedicle of surrounding tissue to the right and left side of the heart respectively. The left internal mammary artery is used for the left anterior descending artery in a skeletonised or non-skeletonised fashion.
The evaluation is made with angiography up to 5 years after surgery.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01310725
|Dept of Cardiothoracic Surgery, Orebro University Hospital|
|Orebro, Sweden, 701 85|
|Study Chair:||Lars Norgren, MD, PhD, Prof.||Orebro University|