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Circadian Rhythm of Blood Lactate

This study has been completed.
Sponsor:
Collaborator:
State University of New York - Downstate Medical Center
Information provided by (Responsible Party):
Axel Schlitt, Martin-Luther-Universität Halle-Wittenberg
ClinicalTrials.gov Identifier:
NCT01303848
First received: February 24, 2011
Last updated: May 1, 2012
Last verified: May 2012
History of Changes
  Purpose

To elucidate whether blood lactate, lipid transfer proteins and PPARs/CLOCK/Bal1 have a circadian rhythm


Condition Intervention
Healthy
 Other: Blood Sampling

Study Type: Observational
Study Design: Time Perspective: Prospective
Official Title: Circadian Rhythm of Blood Lactate, Lipid Transferproteins and Genetic Markers (PPARs, CLOCK, Bmal1)

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by Martin-Luther-Universität Halle-Wittenberg:

Primary Outcome Measures:
  • Circadian rhythm of blood lactate [ Time Frame: 5 months ] [ Designated as safety issue: No ]
    Blood samples


Secondary Outcome Measures:
  • Circadian rhythm of Lipid transfer proteins [ Time Frame: 5 months ] [ Designated as safety issue: No ]
    Blood

  • Circadian rhythm of PPARs, CLOCK and Bal1 [ Time Frame: 5 months ] [ Designated as safety issue: No ]
    Blood


Enrollment: 30
Study Start Date: February 2011
Study Completion Date: May 2012
Primary Completion Date: December 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Healthy probands
Healthy probands, age between 18 and 40 years
 Other: Blood Sampling
Blood Sampling over 24 hours

Detailed Description:

Blood will be drawn fasting and then every hour over a period of 24 hours in 30 healthy probands.

  Eligibility

Ages Eligible for Study:   18 Years to 40 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

30 healthy probands

Criteria

Inclusion Criteria:

  • Age between 18 and 40 years old

Exclusion Criteria:

  • Inability/unwilling to give written informed consent
  • Chronic disease
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01303848

Locations
Germany
University Clinic Halle, Martin Luther-University Halle-Wittenberg
Halle (Saale), Germany, 06120
Sponsors and Collaborators
Martin-Luther-Universität Halle-Wittenberg
State University of New York - Downstate Medical Center
Investigators
Principal Investigator: Axel Schlitt, MD Department of Medicine III, University Clinic Halle, Martin Luther-University Halle-Wittenberg
  More Information

No publications provided

Responsible Party: Axel Schlitt, PD Dr. med. habil., Martin-Luther-Universität Halle-Wittenberg
ClinicalTrials.gov Identifier: NCT01303848     History of Changes
Other Study ID Numbers: UKH2011Sport1
Study First Received: February 24, 2011
Last Updated: May 1, 2012
Health Authority: Germany: Federal Institute for Drugs and Medical Devices

Keywords provided by Martin-Luther-Universität Halle-Wittenberg:
Blood lactate
Lipid transfer proteins
Lactate
PLTP
 CETP
PPARs
CLOCk
Bal1

ClinicalTrials.gov processed this record on May 19, 2013