Safety of Remifentanil Infusion
The effect of maintenance remifentanil infusion with target controlled infusion during laryngeal mask airway removal on hemodynamic parameters and emergence quality is going to be investigated.
|Study Design:||Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Investigator)
Primary Purpose: Treatment
|Official Title:||The Effects of Maintenance a Remifentanil Infusion on the Hemodynamic Variables and Recovery Quality|
- Smooth cLMA Removal Condition (Score 1) [ Time Frame: At the end of the surgery ] [ Designated as safety issue: Yes ]cLMA removal was accepted as successful (score 1) if none of the complications coughing, teeth clenching, gross purposeful movements, breath holding, laryngospasm, and desatura- tion to SpO2\90% was observed. If any of these compli- cations was observed it was regarded as unsuccessful (score 2)
|Study Start Date:||February 2011|
|Study Completion Date:||April 2011|
|Primary Completion Date:||March 2011 (Final data collection date for primary outcome measure)|
Active Comparator: ultiva,remifentanil,opioid,analgesic
Remifentanil:1.5ng/ml remifentanil infusion maintained at the end of the surgery
1-4 ng/mL i.v. infusion during the surgery, maintenance dosage till LMA removal is 1.5 ng/mL.
No Intervention: control
Control:Remifentanil stopped at the end of the surgery
In all patients (control group and remifentanil group induction of anesthesia will be achieved with desflurane and remifentanil.Anesthesia will be maintained with remifentanil (1-4 ng/mL) by TCI target controlled infusion, and desflurane . Throughout the surgery hemodynamic parameters are going to be recorded. As soon as the surgery has been finished, in control group remifentanil infusion and desflurane inhalation is going to be stopped.In remifentanil group,desflurane inhalation is going to be stopped and remifentanil infusion will be maintained until the removal of LMA. During the emergence period the time of eye opening, hemodynamic parameters and emergence quality (score 1-2)are going to be recorded.
|Ministry of Health Diskapi Yildirim Beyazit Research and Training Hospital departement of 1. Anesthesiology|
|Ankara, Turkey, 06110|
|Study Chair:||Jülide Ergil, MD||Ministry of Health Dıskapi Yildirim Beyazit Training and Research Hospital, Anesthesiology 1.|
|Study Chair:||Alp Alptekin, MD||Ministry of Health Diskapi Yildirim Beyazit Training and Research Hospital, Anesthesiology 1|
|Study Chair:||Nihan Aktürk, MD||Ministry of Health Diskapi Yildirim Beyazit Training and Research Hospital , Anesthesiology 1|
|Study Chair:||Haluk Gümüs, MD||Ministry of Health Diskapi Yildirim Beyazit Training and Research Hospital, Anesthesiology 1|