Cognitive Processing Therapy for Combat-related Posttraumatic Stress Disorder (PTSD)

• Posttraumatic Stress Disorder Checklist-Stressor-specific Version (PCL-S) [ Time Frame: Baseline ] [ Designated as safety issue: No ]
  PCL-S measures symptoms of posttraumatic stress disorder in response to a specific stressor.
  
  
• Posttraumatic Stress Disorder Checklist-Stressor-specific Version (PCL-S) [ Time Frame: Once per week for 6 weeks during receipt of the study treatment ] [ Designated as safety issue: No ]
  
• Posttraumatic Stress Disorder Checklist-Stressor-specific Version (PCL-S) [ Time Frame: 2 weeks posttreatment ] [ Designated as safety issue: No ]
  
• Posttraumatic Stress Disorder Checklist-Stressor-specific Version (PCL-S) [ Time Frame: 6 months posttreament ] [ Designated as safety issue: No ]
  
• Posttraumatic Stress Disorder Checklist-Stressor-specific Version (PCL-S) [ Time Frame: 12 months posttreament ] [ Designated as safety issue: No ]
  

Estimates indicate that between 100,000 and 300,000 Operation Iraqi Freedom (OIF) and Operation Enduring Freedom (OEF) veterans are at significant risk for chronic post-traumatic stress disorder (PTSD), which can become a chronic disorder that impacts all areas of a person's life. PTSD treatment programs are being developed throughout the Department of Defense (DoD) and the Veterans Affairs (VA), but because of the large number of Service Members returning from deployment with PTSD, it is often necessary to provide psychotherapy in groups. Cognitive Processing Therapy (CPT), an evidence-based treatment for PTSD, was originally developed as a group-based intervention. However, group-based CPT treatment has never been systematically compared to other forms of group treatment or to individual CPT treatment. The public policy implications of the results of this trial are significant. If both treatment formats are equivalent or if group treatment is better, then group treatment would be a more efficient and cost-effective therapy modality in most cases. On the other hand, if individual therapy is found to be superior, the investment of greater resources into individual therapy will be justified in order to provide the most effective treatment for PTSD to military personnel. The first purpose of this study is to compare group-administered CPT-Cognitive-only version (CPT-C) to Present Centered Therapy (PCT) in order to determine whether the results of CPT exceed those of receiving a therapy that focuses on current problems rather than past trauma in a group format. A second purpose is to conduct a randomized controlled trial to compare group and individual CPT-C for the treatment of PTSD in OIF/OEF military personnel. Four hundred (400) adult male and female active-duty OIF/OEF military personnel over 18 years of age will be enrolled into this study over the course of five years. Approximately 98 participants will receive either group PCT or group CPT-C; the remainder of the participants will be randomized between group and individual CPT-C.