Bleeding Prediction in Patients Following Cardiac Surgery Using Whole Blood Aggregometry and Thromboelastometry
Recruitment status was Recruiting
Use of whole blood impedance aggregometry and rotational thromboelastometry can reveal useful data about platelet function and viscoelastic properties of blood clot in patients undergoing cardiac surgery.
The purpose of this study is to clarify whether it is possible to predict patients on excessive risk of perioperative bleeding using whole blood impedance aggregometry and rotational thromoelastometry.
Antiplatelet therapy is the cornerstone in treatment of patients with coronary artery disease. Another research goal is to determine the degree of response to antiplatelet therapy before and after surgery and to investigate whether patients by level of response to antiplatelet therapy before surgery have a higher risk of perioperative bleeding.
Coronary Artery Disease
Aortic Valve Disease
Mitral Valve Disease
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Bleeding Prediction in Patients Undergoing Cardiac Surgery Using Whole Blood Impedance Aggregometry and Rotational Thromboelastometry|
- Chest tube output in first 24 hours [ Time Frame: 24 hours after surgical procedure ] [ Designated as safety issue: No ]
- Allogenic blood products transfusion [ Time Frame: 7 days after surgery including the day of surgery ] [ Designated as safety issue: No ]
|Study Start Date:||August 2009|
|Estimated Study Completion Date:||March 2012|
|Estimated Primary Completion Date:||January 2011 (Final data collection date for primary outcome measure)|
Patients undergoing elective cardiac surgery
Patients undergoing elective cardiac surgery will be enrolled in study. Data about antiplatelet therapy ingestion prior to surgery will be included.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01281397
|University hospital center Zagreb- Rebro||Recruiting|
|Zagreb, Croatia, 10000|
|Contact: Mate Petricevic, M.D. 0038512367529 email@example.com|
|Contact: Bojan Biocina, M.D., Ph.D 0038512367529 firstname.lastname@example.org|
|Principal Investigator: Mate Petricevic, M.D.|
|Principal Investigator:||Mate Petricevic, M.D.||University hospital center Zagreb- Rebro|
|Study Chair:||Bojan Biocina, M.D., Ph.D.||University hospital center Zagreb - Rebro|