Effects of Exercise With or Without Blueberries on Cardiovascular Risk Markers

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Fredrik H Nystrom, University Hospital, Linkoeping
ClinicalTrials.gov Identifier:
NCT01274078
First received: January 10, 2011
Last updated: July 26, 2012
Last verified: July 2012
  Purpose

About 32 healthy subjects are subjected to 4 weeks of exercise, 4 weeks of washout and 4 weeks of sedentary life style, randomization decides whether they start with exercise or with being "couch potatoes". All participants are also randomized to also consume 150 g of blueberries on exercise days or not. The exercise is constituted of 5 km running 5 days a week during the 4 week period. The exercise period and the "couch" period are started and ended with a 5 km run at maximal speed and the fasting blood samples for cardiovascular risk factors are measured before and after this run, ie 8 times in total.


Condition Intervention
Risk Factors Cardiovascular Disease
Inflammation
Exercise
Sedentary Life
Biological: Blueberries

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Open Label
Primary Purpose: Basic Science
Official Title: Effects of Exercise With or Without Blueberries on Cardiovascular Risk Markers

Resource links provided by NLM:


Further study details as provided by University Hospital, Linkoeping:

Primary Outcome Measures:
  • markers for cardiovascular disease [ Time Frame: 3 months ] [ Designated as safety issue: No ]
    Insulin levels, glucose levels, lipids, hs-CRP, troponin T


Enrollment: 32
Study Start Date: July 2010
Study Completion Date: March 2011
Primary Completion Date: December 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
No Intervention: conventional food
Regular eating habits during exercise period
Active Comparator: Blueberries
Intervention: Addition of blueberries (150g/day) to regular food during the exercise period on days with exercise
Biological: Blueberries
150 grams of frozen blueberries on the same day as exercise

  Eligibility

Ages Eligible for Study:   18 Years to 60 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • healthy subjects

Exclusion Criteria:

  • significant disease and disabilities that hinder running
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01274078

Locations
Sweden
Linkoeping, Sweden
Sponsors and Collaborators
University Hospital, Linkoeping
  More Information

No publications provided

Responsible Party: Fredrik H Nystrom, MD professor, University Hospital, Linkoeping
ClinicalTrials.gov Identifier: NCT01274078     History of Changes
Other Study ID Numbers: FHN_exc_blueberries
Study First Received: January 10, 2011
Last Updated: July 26, 2012
Health Authority: Sweden: Linköping University.

Keywords provided by University Hospital, Linkoeping:
inflammation
lipids
CRP

Additional relevant MeSH terms:
Cardiovascular Diseases
Inflammation
Pathologic Processes

ClinicalTrials.gov processed this record on October 23, 2014