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Glucose, Whey Protein and Time to the Next Meal on Mealtime Food Intake in Children

This study has been completed.
Sponsor:
Collaborator:
Canadian Institutes of Health Research (CIHR)
Information provided by (Responsible Party):
G. Harvey Anderson, University of Toronto
ClinicalTrials.gov Identifier:
NCT01272427
First received: January 6, 2011
Last updated: February 13, 2013
Last verified: February 2013
History of Changes
  Purpose

The investigators hypothesize that glucose and whey protein given 30 and 60 min before a pizza meal will exert different effects on food intake in adolescent children, and will depend on pubertal stage. Food intake will be measured at 30 and 60 min following a glucose(0.75 g of glucose/kg body weight), whey protein (0.75 g of glucose/kg body weight) or sweetened noncaloric beverage. Subjective appetite will be measured as well.


Condition Intervention
Obesity
 Dietary Supplement: water with glucose
Dietary Supplement: water and whey protein
Dietary Supplement: water with noncaloric sweetener

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Single Blind (Subject)
Primary Purpose: Prevention
Official Title: The Effect of Glucose, Whey Protein and Time to the Next Meal on Food Intake and Subjective Appetite in Normal Weight and Overweight/Obese Children

Resource links provided by NLM:

Drug Information available for: Dextrose
U.S. FDA Resources

Further study details as provided by University of Toronto:

Primary Outcome Measures:
  • Food intake (kcal) [ Time Frame: 30 and 60 min after the treatment ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • subjective appetite [ Time Frame: 0-120 min ] [ Designated as safety issue: No ]

Enrollment: 36
Study Start Date: January 2010
Study Completion Date: February 2013
Primary Completion Date: December 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: noncaloric beverage
noncaloric sweetened beverage administered 30 min prior to mealtime
 Dietary Supplement: water with noncaloric sweetener
0.15 g of sucralose added to water
Experimental: noncaloric beverage (60 min)
noncaloric sweetened beverage administered 60 min prior to mealtime
 Dietary Supplement: water with noncaloric sweetener
0.15 g of sucralose added to water
Experimental: glucose beverage
glucose beverage administered 30 min prior to mealtime
 Dietary Supplement: water with glucose
0.75 g/kg body weight of glucose added to water
Experimental: glucose beverage (60 min)
glucose beverage administered 60 min prior to mealtime
 Dietary Supplement: water with glucose
0.75 g/kg body weight of glucose added to water
Experimental: whey protein beverage
whey protein beverage administered 30 min prior to mealtime
 Dietary Supplement: water and whey protein
0.75 g/kg body weight of whey protein added to water
Experimental: whey protein beverage (60 min)
whey protein beverage administered 60 min prior to mealtime
 Dietary Supplement: water and whey protein
0.75 g/kg body weight of whey protein added to water

  Eligibility

Ages Eligible for Study:   9 Years to 14 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • children with no emotional, behavioral or learning problems

Exclusion Criteria:

  • underweight children
  • children with emotional, behavioral or learning problems
  • children who dislike foods in study
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01272427

Locations
Canada, Ontario
Department of Nutritional Sciences
Toronto, Ontario, Canada, M5S 3E2
Sponsors and Collaborators
University of Toronto
Canadian Institutes of Health Research (CIHR)
Investigators
Principal Investigator: Harvey Anderson, PhD University of Toronto
  More Information

No publications provided

Responsible Party: G. Harvey Anderson, Professor, University of Toronto
ClinicalTrials.gov Identifier: NCT01272427     History of Changes
Other Study ID Numbers: FoodIntakeKids_21595
Study First Received: January 6, 2011
Last Updated: February 13, 2013
Health Authority: Canada: Ethics Review Committee

Additional relevant MeSH terms:
Obesity
Overnutrition
Nutrition Disorders
 Overweight
Body Weight
Signs and Symptoms

ClinicalTrials.gov processed this record on May 22, 2013