Temple Registry for the Investigation of African American Gastrointestinal Disease Epidemiology (TRIAGE)
DESCRIPTION: Minimal data exists on the prevalence of gastroesophageal reflux disease in minority populations. Specific objectives of this K24 research project are to: (1) Provide an estimate of the prevalence of gastroesophageal reflux disease in an urban, African American population; (2) Determine whether specific risk factors including diet, tobacco use, physical activity, and psychosocial stress are important in the targeted population. We will also measure height, weight, and waist/hip circumference to determine the impact of central obesity on reflux; (3) To identify the importance of race and identify risk factors for gastroesophageal reflux disease unique to the African Americans population by using a control group composed of Caucasians; PUBLIC HEALTH RELEVANCE: This research will help doctors to understand the frequency and risks for esophageal reflux disease (heartburn) in African Americans.
Gastroesophageal Reflux Disease
Functional Bowel Disorders
|Study Design:||Observational Model: Case Control
Time Perspective: Cross-Sectional
|Official Title:||Temple Registry for the Investigation of African American Gastrointestinal Disease Epidemiology|
- Epidemiologic factors associated with prevalent reflux disease. [ Time Frame: Two years ] [ Designated as safety issue: No ]Patients will complete a series of standardized questionnaires to determine the prevalence of reflux disease and risk factors for its development. We will query diet, depression, drug, tobacco, and alcohol use as well as a variety of other factors. We will study 750 African Americans and have 250 caucasian controls all from the same community in North Philadelphia.
- Longitudinal study on incidence of reflux disease [ Time Frame: 10 years ] [ Designated as safety issue: No ]We will follow the established cohort over 10 years to look at the incidence of reflux disease as well as the incidence of functional bowel disorders in African Americans.
|Study Start Date:||April 2010|
|Estimated Study Completion Date:||June 2020|
|Estimated Primary Completion Date:||January 2020 (Final data collection date for primary outcome measure)|
Consists of 750 African Americans living in the zip code surrounding Temple Hospital between the ages of 18 and 80.
Caucasian comparison group
Consists of 250 Caucasian Americans living in the zip code surrounding Temple Hospital between the ages of 18 and 80.
Show Detailed Description
Please refer to this study by its ClinicalTrials.gov identifier: NCT01262755
|United States, Pennsylvania|
|Temple University Hospital||Recruiting|
|Philadelphia, Pennsylvania, United States, 19140|
|Contact: Amiya Palit, MD 215-707-5477|
|Contact: Frank Friedenberg, MD 215-707-4391 email@example.com|
|Principal Investigator: Frank K Friedenberg, MD|
|Sub-Investigator: Amiya Palit, MD|
|Principal Investigator:||Frank K Friedenberg, MD||Temple University|