Evaluation of Influenza-Specific Immune Responses in Children and Adults During the 2010-2011 Influenza Season in the U.S.

Healthy participants ages 6 years and older who are available for 3 clinic study visits over approximately eight months. Participants must be willing and able to donate blood for storage and research. Females must not be or become pregnant during the study. Multiple subjects from the same household may not be enrolled into the same age group.

Inclusion Criteria:

• Children ages 6 through 17 years and adults 18 years of age or older
• Able to provide proof of identity to the satisfaction of the study clinician completing the enrollment process
• Able and willing to complete the informed consent/assent process
• Willing to donate blood for storage and for research, at least at three study visits
• Willing to have genetic tests performed on stored blood for research purposes

Exclusion Criteria:

• Known to be pregnant.
• Medical, psychiatric, occupational or other condition that, in the judgment of the site investigator, is a contraindication to protocol participation or impairs a subject's ability to give informed consent.
• Bleeding disorder diagnosis or any contraindications to blood drawing as assessed by the site investigator
• Immune system known to be compromised by HIV or other active infection, active cancer, or systemic immunosuppressive treatments.
• Seasonal influenza vaccine within the 12 weeks prior to enrollment.
• Another subject from the same household enrolled into the same age group.