Plantar Faciitis and Diabetes Mellitus (No acronym)
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Purpose
Obesity is a risk factor for calcaneal spur (CS) formation which is supposed to originate from chronic plantar fasciitis. Diabetes mellitus may contribute to the risk of CS by decreased ability of tissue repair and increased reactive ossification. Thus, the investigators aimed to determine CS incidence in asymptomatic obese subjects with and without type 2 diabetes mellitus (T2DM).
| Condition |
|---|
|
Diabetes Mellitus |
| Study Type: | Observational |
| Study Design: | Observational Model: Case Control Time Perspective: Prospective |
| Official Title: | Increased Calcaneal Spur Incidence in Patients With Obesity and Type 2 Diabetes Mellitus |
- Increased Calcaneal Spur Incidence in Patients With Obesity and Type 2 Diabetes Mellitus [ Time Frame: 3 months ] [ Designated as safety issue: Yes ]Calcaneal spur incidence is increased in patients with diabetes mellitus.
| Enrollment: | 93 |
| Study Start Date: | February 2009 |
| Study Completion Date: | March 2009 |
| Groups/Cohorts |
|---|
| diabetic patients |
|
diabetic patients and healty controls
there are two groups in this study. One group is obese type 2 diabetic patiens and other group is healty controls.
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Detailed Description:
OBJECTIVE-Obesity is a risk factor for calcaneal spur (CS) formation which is supposed to originate from chronic plantar fasciitis. Diabetes mellitus may contribute to the risk of CS by decreased ability of tissue repair and increased reactive ossification. Thus, the investigators aimed to determine CS incidence in asymptomatic obese subjects with and without type 2 diabetes mellitus (T2DM).
RESEARCH DESIGN AND METHODS—Ninety-three obese patients with T2DM and forty-two obese subjects without any metabolic disturbances as control were evaluated with lateral calcaneal x-ray in blinded fashion by a radiologist. All participants were informed and written consents have been obtained. Control cases were subjected to 75g glucose challenge test and glucose intolerant subjects were excluded.
RESULTS—T2DM and control groups were statistically similar in mean age (59±10.5 vs. 55±8 yrs, P=0.196, respectively) and mean body mass index (BMI)(35.1±4.3 vs. 33.1±3.3 kg/m2, P=0.073, respectively). Existence of calcaneal spur was 72% in 93 patients (77%) in T2DM group and 24 in 42 (57%) in control group. Groups were significantly different according to existence of CS (P=0.023). Mean age and mean BMI were significantly higher in diabetic patients with calcaneal spur than diabetic patients without calcaneal spur (p=0.001 and p=0.015, respectively). There was positive correlation between existence of calcaneal spur and peripheral neuropathy (p=0,043) in diabetics but no significant relation between existence of CS and glycolysed hemoglobin levels or diabetes duration (all P>0.05).
CONCLUSIONS—Clinicians should pay attention the increased incidence of CS in patients with T2DM to avoid foot complications.
Eligibility| Ages Eligible for Study: | 49 Years to 69 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
| Sampling Method: | Probability Sample |
93 paitents and 42 control group
Inclusion Criteria:
- Clinical diagnosis of Diabetes mellitus
- Must be obese
Exclusion Criteria:
- Previous radiotherapy to the foot,
- previous trauma to the foot (fracture, rupture of tendon),
- rheumatic or vascular diseases,
- malign diseases,
- lymphatic edema.
Contacts and Locations
More Information
No publications provided
| Responsible Party: | Gulhane School of Medicine, Department of Endocrinology and Metabolism |
| ClinicalTrials.gov Identifier: | NCT01259206 History of Changes |
| Other Study ID Numbers: | 11.10.2008/127 |
| Study First Received: | December 13, 2010 |
| Last Updated: | June 17, 2011 |
| Health Authority: | Turkey: Ministry of Health |
Keywords provided by Gulhane School of Medicine:
|
Calcaneal Spur, Diabetic Obese Patients |
Additional relevant MeSH terms:
|
Diabetes Mellitus Diabetes Mellitus, Type 2 Heel Spur Glucose Metabolism Disorders Metabolic Diseases Endocrine System Diseases |
Exostoses Hyperostosis Bone Diseases Musculoskeletal Diseases Foot Diseases |
ClinicalTrials.gov processed this record on May 16, 2013