The Study of Polycystic Ovary Syndrome (PCOS) and Questionnaire
Polycystic ovary syndrome (PCOS) is an extremely common disorder in women of reproductive age. Diagnosis of PCOS is principally based on clinical and physical findings. Diagnostic criteria and PCOS definitions used by clinicians and researchers are almost as heterogeneous as the syndrome. This first part of study is determine whether genetic polymorphisms influence hormonal and metabolic characteristics in Taiwanese patients with PCOS and controls. Furthermore, women with PCOS were reported with high risk of cardiovascular disease, the investigators planned to calculate the difference of carotid intima-media thickness (IMT) and B-type natriuretic peptide (BNP) between women with PCOS and normal control to determine the premature atherosclerosis of women with PCOS.
Polycystic Ovary Syndrome
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||The Study of Polycystic Ovary Syndrome (PCOS) and Questionnaire|
- Obesity is the predominant predictor of impaired glucose tolerance and metabolic disturbance in polycystic ovary syndrome. [ Time Frame: Prospectively study in University teaching hospital from 31 August 2010 to 31 August 2011. ] [ Designated as safety issue: No ]To evaluate the contribution to glucose intolerance and metabolic syndrome of obesity combined with the diagnostic criteria of polycystic ovary syndrome (PCOS).
Biospecimen Retention: Samples Without DNA
|Study Start Date:||November 2010|
|Study Completion Date:||January 2013|
|Primary Completion Date:||January 2013 (Final data collection date for primary outcome measure)|
Polycystic Ovary Syndrome.
Polycystic ovary syndrome was diagnosed according to the 2003 Rotterdam criteria, which require a minimum of two of the following three criteria: PCOM, chronic anovulation and hyperandrogenism.
Normal control women were women who did not present with any of three PCOS criteria.
|Taipei Medical University-WanFang Hospital|
|Principal Investigator:||Ming-I Hsu||Taipei Medical University WanFang Hospital|