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IOP Lowering Effects of Topical Anesthetics Used Frequently in the Ophthalmology Clinic

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
University of Nebraska
ClinicalTrials.gov Identifier:
NCT01254149
First received: December 2, 2010
Last updated: June 13, 2012
Last verified: June 2012
History of Changes
  Purpose

The primary purpose of this study is to determine whether topical ophthalmic anesthetics lower the intraocular pressure in the eye.


Condition
Normal Tension Glaucoma

Study Type: Observational
Study Design: Time Perspective: Cross-Sectional
Official Title: Intraocular Pressure Lowering Effects of Topical Anesthetics Used Frequently in the Ophthalmology Clinic

Resource links provided by NLM:

MedlinePlus related topics: Glaucoma
U.S. FDA Resources

Further study details as provided by University of Nebraska:

Primary Outcome Measures:
  • Measured pressures in subjects' eyes with and without anesthetics. [ Time Frame: 30 minutes ] [ Designated as safety issue: No ]

Enrollment: 43
Study Start Date: January 2011
Study Completion Date: April 2012
Primary Completion Date: April 2012 (Final data collection date for primary outcome measure)
  Show Detailed Description

  Eligibility

Ages Eligible for Study:   19 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Subjects 19 years of age and older with normal eyes and with ocular disease.

Criteria

Inclusion Criteria:

  • Subjects must be 19 years of age and older

Exclusion Criteria:

  • Corneal diseases including corneal transplants, corneal dystrophies, or trauma to the cornea that may prevent reliable tonometry of either eye.
  • Intolerant to topical Proparacaine and Benoxinate
  • Pregnant or nursing
  • 18 years of age and younger.
  • Physical limitation preventing ability to obtain reliable intraocular measurements (e.g. difficulty positioning subjects in front of the slit lamp or inability to keep eyes open during the intraocular pressure checks).
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01254149

Locations
United States, Nebraska
University of Nebraska Medical Center, Department of Ophthalmology
Omaha, Nebraska, United States, 68198
Sponsors and Collaborators
University of Nebraska
Investigators
Principal Investigator: Nathan Welch, MD UNMC Department of Ophthalmology and Visual Sciences
  More Information

No publications provided

Responsible Party: University of Nebraska
ClinicalTrials.gov Identifier: NCT01254149     History of Changes
Other Study ID Numbers: 577-10-FB
Study First Received: December 2, 2010
Last Updated: June 13, 2012
Health Authority: United States: Institutional Review Board

Additional relevant MeSH terms:
Glaucoma
Low Tension Glaucoma
Ocular Hypertension
Eye Diseases
Optic Nerve Diseases
Anesthetics
Anesthetics, Local
 Central Nervous System Depressants
Physiological Effects of Drugs
Pharmacologic Actions
Central Nervous System Agents
Therapeutic Uses
Sensory System Agents
Peripheral Nervous System Agents

ClinicalTrials.gov processed this record on May 19, 2013