Saccadic Eye Movements Are Impaired In Glaucoma
This study is enrolling participants by invitation only.
Sponsor:
St. Michael's Hospital, Toronto
Information provided by (Responsible Party):
Neera Gupta, St. Michael's Hospital, Toronto
ClinicalTrials.gov Identifier:
NCT01254058
First received: December 2, 2010
Last updated: January 3, 2013
Last verified: January 2013
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Purpose
The purpose of this study is to determine whether rapid eye movements called saccades are impaired in glaucoma, a neurodegenerative disease of visual pathways.
| Condition |
|---|
|
Glaucoma, Open-Angle |
| Study Type: | Observational |
| Study Design: | Observational Model: Case Control Time Perspective: Prospective |
| Official Title: | Novel Vision Testing Paradigms for Patients With Glaucoma |
Resource links provided by NLM:
Genetics Home Reference related topics:
early-onset glaucoma
MedlinePlus related topics:
Glaucoma
U.S. FDA Resources
Further study details as provided by St. Michael's Hospital, Toronto:
Primary Outcome Measures:
- Delay in saccades [ Time Frame: April 2014 ] [ Designated as safety issue: No ]
| Enrollment: | 40 |
| Study Start Date: | July 2010 |
| Estimated Study Completion Date: | April 2014 |
| Estimated Primary Completion Date: | April 2014 (Final data collection date for primary outcome measure) |
| Groups/Cohorts |
|---|
| Glaucoma Group |
| Age-Matched Controls |
Detailed Description:
Eye movements that quickly scan a visual scene are critical to a number of daily activities including driving. It is not known whether rapid eye movement called saccades, are altered in glaucoma.
Eligibility| Ages Eligible for Study: | 40 Years to 80 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Study Population
19 glaucoma patients and 21 age-matched controls will be identified and consented.
Criteria
Inclusion Criteria:
- Ages from 40-80 years. Primary open angle glaucoma is defined by characteristic glaucomatous optic nerve head findings and the presence of corresponding visual field deficits in one or both eyes. All control subjects will be age-matched, with no ocular medical or surgical history, and a completely normal eye examination. Age-matched controls will be recruited from local hospital personnel and accompanying relatives.
Exclusion criteria:
- Any patient with a history of other eye disease, neurological disease or neurodegenerative disorder, or history of incisional ocular surgery within the previous month will be excluded.
Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01254058
Locations
| Canada, Ontario | |
| St. Michael's Hospital | |
| Toronto, Ontario, Canada, M5B 1W8 | |
Sponsors and Collaborators
St. Michael's Hospital, Toronto
Investigators
| Principal Investigator: | Neeru Gupta, MD, PhD | St. Michael's Hospital, Toronto |
More Information
Publications:
| Responsible Party: | Neera Gupta, Dr. Neeru Gupta, St. Michael's Hospital, Toronto |
| ClinicalTrials.gov Identifier: | NCT01254058 History of Changes |
| Other Study ID Numbers: | REB 06-056 |
| Study First Received: | December 2, 2010 |
| Last Updated: | January 3, 2013 |
| Health Authority: | Canada: Ethics Review Committee |
Additional relevant MeSH terms:
|
Glaucoma Glaucoma, Open-Angle Ocular Hypertension Eye Diseases |
ClinicalTrials.gov processed this record on May 16, 2013