Saccadic Eye Movements Are Impaired In Glaucoma
This study is enrolling participants by invitation only.
Information provided by (Responsible Party):
Neera Gupta, St. Michael's Hospital, Toronto
First received: December 2, 2010
Last updated: January 3, 2013
Last verified: January 2013
The purpose of this study is to determine whether rapid eye movements called saccades are impaired in glaucoma, a neurodegenerative disease of visual pathways.
||Observational Model: Case Control
Time Perspective: Prospective
||Novel Vision Testing Paradigms for Patients With Glaucoma
Primary Outcome Measures:
- Delay in saccades [ Time Frame: April 2014 ] [ Designated as safety issue: No ]
| Study Start Date:
| Estimated Study Completion Date:
| Estimated Primary Completion Date:
||April 2014 (Final data collection date for primary outcome measure)
Eye movements that quickly scan a visual scene are critical to a number of daily activities including driving. It is not known whether rapid eye movement called saccades, are altered in glaucoma.
|Ages Eligible for Study:
||40 Years to 80 Years
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
19 glaucoma patients and 21 age-matched controls will be identified and consented.
- Ages from 40-80 years. Primary open angle glaucoma is defined by characteristic glaucomatous optic nerve head findings and the presence of corresponding visual field deficits in one or both eyes. All control subjects will be age-matched, with no ocular medical or surgical history, and a completely normal eye examination. Age-matched controls will be recruited from local hospital personnel and accompanying relatives.
- Any patient with a history of other eye disease, neurological disease or neurodegenerative disorder, or history of incisional ocular surgery within the previous month will be excluded.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01254058
|St. Michael's Hospital
|Toronto, Ontario, Canada, M5B 1W8 |
St. Michael's Hospital, Toronto
||Neeru Gupta, MD, PhD
||St. Michael's Hospital, Toronto
||Neera Gupta, Dr. Neeru Gupta, St. Michael's Hospital, Toronto
History of Changes
|Other Study ID Numbers:
|Study First Received:
||December 2, 2010
||January 3, 2013
||Canada: Ethics Review Committee
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on May 16, 2013