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A Research on the Hospital Pollution Control and Hygine Intervention of Chemotherapy Drugs Exposure

The recruitment status of this study is unknown because the information has not been verified recently.
Verified December 2010 by Taipei Medical University WanFang Hospital.
Recruitment status was  Active, not recruiting
Sponsor:
Information provided by:
Taipei Medical University WanFang Hospital
ClinicalTrials.gov Identifier:
NCT01253057
First received: December 1, 2010
Last updated: NA
Last verified: December 2010
History: No changes posted
  Purpose

Several epidemiological studies found that exposure to antineoplastic agents were associated with some reproductive, carcinogenic effects, higher rates of advance micronuclei (MN), sister-chromatic-exchange (SCE) and spontaneous abortion. Cleaning staff were potentially exposed to these agents while cleaning ward, ward toilet or other area.

One medical center and one area hospitals in Taipei.Surface wipe samples were collected in the cleaning staff work area, such as ward environment and ward toilet. Urine and blood samples of subjects were collected for exposure examinations. Platinum-containing drugs (Cisplatin, Carboplatin, Oxaliplatin) were used as indicator drugs in environmental (surface wipe samples) and biological (urine and blood samples) samples.

A self-administered questionnaire was used to collect demographic data, working practices, medical and contact history, and perceived work-related symptoms of cleaning staff.

The results of this study will be to reduce exposure to cleaning staff.


Condition
Sister-chromatic-exchange(SCE)
Micronuclei(MN)

Study Type: Observational
Study Design: Observational Model: Case Control
Official Title: A Research on the Hospital Pollution Control and Hygine Intervention of Chemotherapy Drugs Exposure

Further study details as provided by Taipei Medical University WanFang Hospital:

Estimated Enrollment: 200
Study Start Date: October 2010
Estimated Study Completion Date: December 2011
Groups/Cohorts
Experimental Group
Control Group

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population

cleaning staff

Criteria

Inclusion Criteria:

  • Only included those who signed the consent study

Exclusion Criteria:

  • none
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01253057

Locations
Taiwan
Taipei Medical University WanFang Hospital
Taipei, Taiwan
Sponsors and Collaborators
Taipei Medical University WanFang Hospital
Investigators
Principal Investigator: Ruey-Yu Chen Taipei Medical University
  More Information

No publications provided

Responsible Party: Ruey-Yu Chen, Taipei Medical University School of Public Health
ClinicalTrials.gov Identifier: NCT01253057     History of Changes
Other Study ID Numbers: 99061
Study First Received: December 1, 2010
Last Updated: December 1, 2010
Health Authority: Taiwan: Department of Health

Keywords provided by Taipei Medical University WanFang Hospital:
cleaning staff
antineoplastic agents

Additional relevant MeSH terms:
Antineoplastic Agents
Therapeutic Uses
Pharmacologic Actions

ClinicalTrials.gov processed this record on May 19, 2013