Evaluation of Anatomic and Visual Outcomes of Initially Closed Macular Holes
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Purpose
To evaluate the anatomic and visual outcomes in patients with initially closed macular holes after vitreoretinal surgery and with one to seven years of follow-up.
| Condition |
|---|
|
Macular Holes |
| Study Type: | Observational |
| Study Design: | Observational Model: Cohort Time Perspective: Retrospective |
| Official Title: | Study of the Anatomic and Visual Outcomes in Patients With Initially Closed Macular Holes After Vitreoretinal Surgery |
| Enrollment: | 79 |
| Study Start Date: | March 2010 |
| Study Completion Date: | May 2010 |
| Primary Completion Date: | May 2010 (Final data collection date for primary outcome measure) |
In recent years, peeling of the internal limiting membrane (ILM) has been used as a supplementary treatment to reducing the tangential tractional forces and inducing hole closure in macular hole surgery, and thus the anatomic success rate has increased to over 90%. However, despite these high rates of surgical success, the reopening of initially closed macular holes has also been observed from the first month to several years following surgery. Because about 45% to 95% of phakic patients frequently develop a progressive nuclear sclerosis cataract after macular hole surgery and require combined or subsequent cataract extraction to improve visual acuity, cataract extraction has become a potential factor in causing macular hole reopening, although this is still under debate. The purpose of this study is to describe the long-term anatomic and visual outcomes in patients who had initial anatomic success with macular hole surgery and who had postoperative follow-up of one or more years. All patient's charts were reviewed for age, macular hole stage (using the Gass classification), macular hole duration, epiretinal membrane of macula presence, ILM peeling, preoperative and postoperative visual acuity, rate of macular hole reopening, cataract extraction, and length of follow-up after vitrectomy.
Eligibility| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Probability Sample |
Patients with initially closed macular holes after vitreoretinal surgery and with one to seven years of follow-up
Inclusion Criteria:
- successful closure of a macular hole after initial vitreoretinal surgery
- a follow-up of at least one year
Exclusion Criteria:
- post-traumatic holes,
- myopic macular holes,
- macular holes associated with a rhegmatogenous retinal detachment,
- eyes with silicone oil tamponade.
Contacts and Locations| China, Guangdong | |
| Zhongshan Ophthalmic Center, Sun Yat-sen University | |
| Guangzhou, Guangdong, China, 510060 | |
| Study Chair: | Shaochong Zhang, MD | Zhongshan Ophthalmic Center, Sun Yat-sen University |
More Information
No publications provided
| Responsible Party: | Shaochong Zhang, Zhongshan Ophthalmic Center, Sun Yat-sen University |
| ClinicalTrials.gov Identifier: | NCT01229657 History of Changes |
| Other Study ID Numbers: | SunYat-senU, 2008B030301306, 2007B031302007 |
| Study First Received: | October 27, 2010 |
| Last Updated: | October 27, 2010 |
| Health Authority: | China: Ethics Committee |
Keywords provided by Sun Yat-sen University:
|
Reopening of macular hole; Visual acuity; Phacoemulsification cataract surgery; Vitrectomy |
Additional relevant MeSH terms:
|
Retinal Perforations Retinal Diseases Eye Diseases |
ClinicalTrials.gov processed this record on June 18, 2013