Evaluation of Donated Human Embryos Following in Vitro Fertilization
Couples who have created excess embryos while undergoing IVF procedures, and who do not wish to transfer those embryos or donate them to another couple may donate the extra embryos to research. The embryos are then used to develop improved laboratory techniques and conditions as well as testing the proficiency of laboratory staff.
Validation of Laboratory Techniques
Validation of Laboratory Methods
Assessment of Laboratory Staff Proficiency
|Study Design:||Time Perspective: Prospective|
|Official Title:||Evaluation of Donated Human Embryos for Study of Normal and Abnormal Differentiation and Development Following in Vitro Fertilization.|
- Freezing methods for embryos [ Time Frame: duration of the study ] [ Designated as safety issue: No ]To test, standardize and implement better methods for the freezing of embryos prior to these techniques being implemented in the clinical setting.
- Development of New Methods [ Time Frame: duration of the study ] [ Designated as safety issue: No ]The development of new methods to optimize the determination of genes and chromosomes in embryos
Biospecimen Retention: Samples With DNA
|Study Start Date:||July 2005|
|Estimated Study Completion Date:||December 2016|
|Estimated Primary Completion Date:||December 2015 (Final data collection date for primary outcome measure)|
Undergoing IVF treatment often results in the production of more embryos than can safely be transferred at one time. These extra embryos are often cryopreserved for future use. In the event that a couple decides that they do not want to proceed with using cryopreserved embryos, these embryos can be discarded, donated to another couple, or donated to research.
Embryos that are donated to research are used to identify a group of parameters that have significant predictive value for assisted reproductive technology outcomes. We hope to develop future laboratory techniques as we gain a better knowledge of gamete development, fertilization and implantation. We will test, standardize and implement better methods for freezing embryos prior to employing these techniques in a clinical setting. We hope to develop new methods to optimize the determination of genes and chromosomes in embryos. We will test the proficiency of laboratory staff on techniques and/or procedures done in the IVF laboratory. This study WILL NOT:create embryos for research, transfer embryos to an individual, develop cell lines or clones.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01219361
|United States, Connecticut|
|Reproductive Medicine Associates of Connecticut|
|Norwalk, Connecticut, United States, 06850|
|United States, Michigan|
|Reproductive Medicine Associates of Michigan|
|Troy, Michigan, United States, 48084|
|United States, New Jersey|
|Reproductive Medicine Assoicates of New Jersey|
|Morristown, New Jersey, United States, 07690|
|United States, New York|
|Reproductive Medicine Associates of New York|
|New York, New York, United States, 10022|
|United States, Pennsylvania|
|Reproductive Medicine Assoicates of PA at Lehigh Valley|
|Allentown, Pennsylvania, United States, 18104|
|Principal Investigator:||Richard T Scott, MD||Reproductive Medicine Associates of New Jersey|