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The Role of Mechanical Stress and Muscle Fatigue in Strength Gains

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Universitaire Ziekenhuizen Leuven
ClinicalTrials.gov Identifier:
NCT01216774
First received: October 6, 2010
Last updated: June 15, 2012
Last verified: September 2010
  Purpose

The purpose of this study is to compare the impact of different levels of mechanical stress and muscle fatigue in strength training conditions on muscle strength, muscle mass and inflammatory processes.


Condition Intervention
Strength Training
Muscle Strength, Muscle Mass, Inflammatory Processes
Other: Strength training

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single Blind (Subject)

Resource links provided by NLM:


Further study details as provided by Universitaire Ziekenhuizen Leuven:

Primary Outcome Measures:
  • Force-velocity characteristics of knee extensors with biodex dynamometer [ Time Frame: Pre and post intervention ] [ Designated as safety issue: No ]

Enrollment: 36
Study Start Date: September 2010
Primary Completion Date: December 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Low load + fatigue Other: Strength training

Leg extension exercise:

Experimental: 60 repetitions at 20-25% of 1RM, 10-12 repetitions at 40% of 1RM Active Comparator: 10-12 repetitions at 80% of 1RM Placebo Comparator: 10-12 repetitions at 40% of 1RM

Active Comparator: High load Other: Strength training

Leg extension exercise:

Experimental: 60 repetitions at 20-25% of 1RM, 10-12 repetitions at 40% of 1RM Active Comparator: 10-12 repetitions at 80% of 1RM Placebo Comparator: 10-12 repetitions at 40% of 1RM

Placebo Comparator: Low load Other: Strength training

Leg extension exercise:

Experimental: 60 repetitions at 20-25% of 1RM, 10-12 repetitions at 40% of 1RM Active Comparator: 10-12 repetitions at 80% of 1RM Placebo Comparator: 10-12 repetitions at 40% of 1RM


  Eligibility

Ages Eligible for Study:   20 Years to 30 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

-

Exclusion Criteria:

  • Knee pathology
  • Systematic training
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01216774

Locations
Belgium
Faculty of Kinesiology and Rehabilitation Sciences
Leuven, Belgium, 3001
Sponsors and Collaborators
Universitaire Ziekenhuizen Leuven
  More Information

No publications provided

Responsible Party: Universitaire Ziekenhuizen Leuven
ClinicalTrials.gov Identifier: NCT01216774     History of Changes
Other Study ID Numbers: S52680
Study First Received: October 6, 2010
Last Updated: June 15, 2012
Health Authority: Belgium: Ethics Committee

ClinicalTrials.gov processed this record on November 25, 2014