Non-Specific Chronic Back Pain; Insight From Spatial Aspects of Lumbar Spinal Muscle Activation

This study is enrolling participants by invitation only.
Sponsor:
Information provided by:
Oslo University Hospital
ClinicalTrials.gov Identifier:
NCT01214213
First received: October 1, 2010
Last updated: April 14, 2011
Last verified: April 2011
  Purpose

There is evidence for altered muscle activity patterns in individuals with non-specific chronic back pain (NSCBP). It is unknown why these alterations in activation pattern occur and how they may be linked to pain experience and to the development of CNSBP. The main objective of this study is to investigate the spatial aspects of muscle activation in relation to fatigue/endurance and CNSBP. A novel approach, utilizing a new multi-channel surface-EMG (MCsEMG) technique will be applied in this project to get insight in fundamental mechanisms related to motor control and fatigue/endurance. In this project data from healthy persons and from patients with NSCBP will be collected and analyzed. NSCBP patients will be compared to healthy persons. To minimize heterogeneity between groups the subject's age range will be from 30 - 50 years. The investigators main hypothesis is that motor control mechanisms of the lumbar muscles are disturbed in NSCBP patients compared to normals, explaining the reduced tolerance for static postures. There has been little investigation of the lumbar musculature with MCsEMG recordings. The lumbar musculature has a complex organization; many, relatively small muscles, in a restricted area. Utilizing two HDsEMG grids with 252 Ag/AgCl contacts will be the superior non-invasive method to investigate motor control mechanisms in this region, and further the investigators understanding of neuromuscular adaptations related to NSCBP. The project may demonstrate changes that will lead us to new insight and new strategies for the treatment of back pain.


Condition Phase
Low Back Pain
Phase 1

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional
Official Title: NON-SPECIFIC CHRONIC BACK PAIN; INSIGHT FROM SPATIAL ASPECTS OF LUMBAR SPINAL MUSCLE ACTIVATION

Resource links provided by NLM:


Further study details as provided by Oslo University Hospital:

Estimated Enrollment: 60
Study Start Date: September 2009
Estimated Primary Completion Date: January 2012 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   30 Years to 50 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Chronic non-spesific low back pain and healthy control subjects

Criteria

Inclusion Criteria:

  • patients
  • diagnosed with chronic NSCBP >3 months duration
  • healthy controls
  • no back pain.

Exclusively exclusion criteria for this group will be back pain in the previous year or back pain lasting longer than one week in previous 3 years.

Exclusion Criteria:

  • anamnesis of medical or drug abuse
  • surgery on the musculoskeletal system of the trunk
  • known congenital malformation of the spine or scoliosis
  • body mass index >27 kg/m2
  • systemic-neurological-degenerative disease
  • history of stroke
  • psychiatric disorder
  • pregnancy and abnormal blood pressure.
  Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT01214213

Locations
Norway
Vestfold Hospital Trust, Kysthospitalet
Stavern, Norway, 3291
Sponsors and Collaborators
Oslo University Hospital
Investigators
Study Chair: Aage Indahl, Phd
  More Information

No publications provided

Responsible Party: Inge Ringheim, Vestfold Hospital Trust, Kysthospitalet, Clinic Physical Medicine and Rehabilitation
ClinicalTrials.gov Identifier: NCT01214213     History of Changes
Other Study ID Numbers: MULTI2009
Study First Received: October 1, 2010
Last Updated: April 14, 2011
Health Authority: Norway:National Committee for Medical and Health Research Ethics

Additional relevant MeSH terms:
Back Pain
Low Back Pain
Pain
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms

ClinicalTrials.gov processed this record on August 01, 2014