Effect of the Consumption of a Fermented Milk on Common Infections in Children Aged 3-6 Years, Attending Day Care Centers
This multicentric, randomized, double-blind and controlled study aims to examine the effect of a fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel® = tested product) on the incidence of respiratory and gastro-intestinal common infectious diseases (cumulated number of infections during the intervention period: primary criteria) in children aged 3-6 years, attending day care centers.Volunteers received either 200g/day of tested product (N=300) or control product (N=299) for 3-months, followed by a 1-month follow-up.
Common Infectious Diseases, Occuring in Healthy Children,
Including Upper Respiratory Tract Infections (Defined as
Rhinopharyngitis, Sore Throat, Sinusitis and Otitis), Lower
Respiratory Tract Infections (Defined as Bronchitis,
Pneumopathy and Flu and Flu-like Syndromes), and
Gastrointestinal Tract Infection Defined as Gastroenteritis.
Other: 1-Fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel®)
Other: 2-Non fermented dairy product (control)
|Study Design:||Allocation: Randomized
Primary Purpose: Basic Science
|Official Title:||Effect of the Consumption of a Fermented Milk on Common Infections in Children Aged 3-6 Years, Attending Day Care Centers|
Please refer to this study by its ClinicalTrials.gov identifier: NCT01200173
|Federal State Institution "Federal research center of pediatric hematology, oncology and imunology"|
|Moscow, Russian Federation, 117997|