Effectiveness of Rupture of Schatzki's Ring Using Biopsy Forceps Versus SIngle Dilation
Recruitment status was Not yet recruiting
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Purpose
Dysphagia is a common reason for referal to the investigators Gastoenterology service. As many as 14% of patients undergoing radiological studies for dysphagia are found to have schatzki rings. Current recommendations for treatment of patients with symptomatic Schatzki rings are based on ancedotal experience and uncontrolled studies. The only randomized study on comparison of techniques the investigators were able to locate was published in 2000 and included only 26 patients. This study demonstrated that the biopsy techinque was as effective as and better tolerated than the standard dilation technique. Considering that the cost and time required for dilatation is greater than the basic biopsy technique, significant cost savings could be achieved using the biopsy technique. As well, patient satisfaction is an important factor considering that Schatzki rings can recur and repeated endoscopy is often required. Therefore, a study that shows a technique to be as or better than the current standard in effectiveness, cost, time, and patient comfort could lead to shift in current practice.
| Condition | Intervention |
|---|---|
|
Dysphagia Schatzki Ring |
Procedure: Biopsy Procedure: Dilation |
| Study Type: | Interventional |
| Study Design: | Allocation: Randomized Endpoint Classification: Efficacy Study Intervention Model: Single Group Assignment Masking: Open Label Primary Purpose: Treatment |
| Official Title: | Effectiveness of Rupture of Schatzki's Ring Using Biopsy Forceps Versus SIngle Dilation |
- Effectiveness of biopsy vs dilation
| Arms | Assigned Interventions |
|---|---|
| Active Comparator: Biopsy Arm | Procedure: Biopsy |
| Active Comparator: Dilation Arm | Procedure: Dilation |
Eligibility| Ages Eligible for Study: | 18 Years to 80 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- Presenting to endoscopy unit with symptoms of dysphagia or known history of schatzki ring
Exclusion Criteria:
- Prior esophageal or gastric surgery, severe esophagitis, coagulopathy
Contacts and Locations| Contact: Michael Curley, MD, FRCPC | 9024043511 | ma_curley@hotmail.com |
| Canada, Nova Scotia | |
| VG Hospital-Capital District Health Authority | Not yet recruiting |
| Halifax, Nova Scotia, Canada, B3H2Y9 | |
| Contact: Michael Curley, MD, FRCPC 9024043511 ma_curley@hotmail.com | |
| Contact: Mark MacMillan, MD, FRCPC 9024732222 mamacmil@dal.ca | |
More Information
No publications provided
| Responsible Party: | Dr. Michael Curley, Division of Gastroenterology, Department of Medicine |
| ClinicalTrials.gov Identifier: | NCT01200147 History of Changes |
| Other Study ID Numbers: | Schatzki-2010 |
| Study First Received: | September 10, 2010 |
| Last Updated: | September 10, 2010 |
| Health Authority: | Canada: Capital Heath Research Ethics Board |
Additional relevant MeSH terms:
|
Deglutition Disorders Rupture Esophageal Diseases Gastrointestinal Diseases |
Digestive System Diseases Pharyngeal Diseases Otorhinolaryngologic Diseases Wounds and Injuries |
ClinicalTrials.gov processed this record on May 22, 2013