The Relationship Between Dietary Habit and Gastroesophageal Flap Valve Abnormality
Recruitment status was Recruiting
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Purpose
Gastroesophageal reflux disease (GERD) is commonly seen in Western countries; however, it is gaining prevalence in Asia countries recently. In addition to the lower esophageal sphincter and the crural fibers of the diaphragm, the flap valve at the gastroesophageal junction is also responsible for maintaining an antireflux barrier. Hill et al developed a grading system of gastroesophageal flap valve (GEFV) and concluded that this flap valve system is simple, reproducible, and offers diagnostic aid in the evaluation of patients with suspicious reflux disease undergoing esophagogastroduodenoscopy (EGD). It is a common belief that large meals provoke considerable postprandial reflux and it results from an increase in the rate of transient lower esophageal sphincter relaxations. One study also revealed that rapid food intake produces more gastroesophageal reflux in healthy volunteers. So this study attempted to evaluate the relationship between dietary habit and GEFV abnormality. The investigators used a questionnaire regarding the dietary habit to the population undergoing EGD in a self-paid health examination.
| Condition |
|---|
|
Healthy Subjects |
| Study Type: | Observational |
| Study Design: | Observational Model: Cohort Time Perspective: Prospective |
| Official Title: | The Relationship Between Dietary Habit and Gastroesophageal Flap Valve Abnormality |
- Grading of Gastroesophageal Flap Valve by Esophagoduodenoscopy [ Time Frame: 1 year ] [ Designated as safety issue: No ]
- Dietary habit questionnaire [ Time Frame: 1 year ] [ Designated as safety issue: No ]
| Estimated Enrollment: | 600 |
| Study Start Date: | August 2010 |
| Estimated Study Completion Date: | December 2011 |
| Estimated Primary Completion Date: | July 2011 (Final data collection date for primary outcome measure) |
| Groups/Cohorts |
|---|
| population undergoing EGD in health examination. |
Eligibility| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | Yes |
| Sampling Method: | Probability Sample |
healthy subjects
Inclusion Criteria:
- The healthy subjects undergo EGD in a self-paid health examination in WanFang Hospital.
Exclusion Criteria:
- None
Contacts and Locations| Taiwan | |
| Yung-Fa Chen | Recruiting |
| Taipei, Taiwan, 116 | |
| Contact: Yung FA Chen, MD 8862968718572 brother.fa@sn.tpemail.net.tw | |
| Principal Investigator: | Yung-Fa Chen, M.D. | Taipei Medical University WanFang Hospital |
More Information
No publications provided
| Responsible Party: | Yung-Fa Chen M.D., Taipei Medical University WanFang Hospital |
| ClinicalTrials.gov Identifier: | NCT01194544 History of Changes |
| Other Study ID Numbers: | 99033 |
| Study First Received: | August 10, 2010 |
| Last Updated: | March 6, 2011 |
| Health Authority: | Taiwan: Department of Health |
Additional relevant MeSH terms:
|
Congenital Abnormalities Food Habits Habits |
ClinicalTrials.gov processed this record on June 17, 2013