Effect of Structural Remodeling on Scar Formation as Assessed by DE-MRI of the Left Atrium (RADAR)
The purpose of this study is to evaluate the impact of pre-ablation fibrosis on scar formation in the left atrium of the heart. This will be assessed by delayed enhancement magnetic resonance imaging and will be looked at in patients who have undergone successful open irrigated cooled-tipped radio-frequency ablation of paroxysmal atrial fibrillation. Follow-up after ablation will be for 12 months.
|Study Design:||Observational Model: Cohort
Time Perspective: Retrospective
|Official Title:||RADAR: Effect of Structural Remodeling on Scar Formation as Assessed by DE-MRI of the Left Atrium Following Open-Irrigation Cooled-Tip Radiofrequency Catheter Ablation of Paroxysmal Atrial Fibrillation|
- Left Atrial (LA) Remodeling Pre-ablation [ Time Frame: Once pre-ablation ] [ Designated as safety issue: No ]Utah staging for fibrosis (I - <=5%, II - 5.01%-20.0%, III - 20.01%-35% and IV - >=35.01%)
|Study Start Date:||August 2010|
|Study Completion Date:||June 2011|
|Primary Completion Date:||June 2011 (Final data collection date for primary outcome measure)|
Those individuals who had an ablation using open irrigation cooled-tip RF ablation.
Show Detailed Description
Please refer to this study by its ClinicalTrials.gov identifier: NCT01187914
|Principal Investigator:||Nassir F Marrouche, MD||University of Utah|