Prediction of Pain in Total Knee Arthroplasty
In this consecutive, prospective cohort study trial the investigators evaluate if preoperative pain response upon heat stimulation is predictive for acute and subacute postoperative pain after total knee arthroplasty.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Is Preoperative Pain Response Upon Tonic Heat Stimulation Predictive for Pain After Total Knee Arthroplasty?|
- Cumulated pain (from 0-24 hours after surgery) [ Time Frame: 24 hours ] [ Designated as safety issue: No ]Pain during walk 5 m (VAS)
- Cumulated pain (from day 1 to day 7 after surgery) [ Time Frame: 7 days ] [ Designated as safety issue: No ]
- Pain at day 14 after surgery [ Time Frame: 14 days ] [ Designated as safety issue: No ]
- Pain at day 30 after surgery [ Time Frame: 30 days ] [ Designated as safety issue: Yes ]
Biospecimen Retention: Samples With DNA
|Study Start Date:||August 2010|
|Study Completion Date:||September 2011|
|Primary Completion Date:||September 2011 (Final data collection date for primary outcome measure)|
|Patiens operated with TKA||
Procedure: Preoperative heat stimulation
Preoperative short and long tonic heat stimulation
The preoperative heat stimulation consists of short and long tonic heat stimulation. Pain response is evaluated with an electronic visual analog scale.
Furthermore the investigators evaluate other factors possibly predictable for acute and subacute postoperative pain after total knee arthroplasty - demographic factors, preoperative pain related factors, psychosocial factors (Hospital Anxiety and Depression Scale and Pain Catastrophizing Scale).
Please refer to this study by its ClinicalTrials.gov identifier: NCT01179204
|Hvidovre University Hospital|
|Copenhagen, Hvidovre, Denmark, 2650|
|Principal Investigator:||Troels H. Lunn, M.D||Hvidovre University Hospital|