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Cognitive Remediation and Functional Skills Training in Schizophrenia

The recruitment status of this study is unknown because the information has not been verified recently.
Verified August 2010 by National Alliance for Research on Schizophrenia and Depression.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
National Alliance for Research on Schizophrenia and Depression
ClinicalTrials.gov Identifier:
NCT01175642
First received: August 3, 2010
Last updated: August 4, 2010
Last verified: August 2010
History of Changes
  Purpose

This randomized trial is examining whether a treatment called cognitive remediation is more effective when it is paired with a social and functional skills training component.


Condition Intervention Phase
Schizophrenia
Schizoaffective Disorder
 Behavioral: Cognitive Remediation
Behavioral: FAST
 Phase 0

Study Type: Interventional
Study Design: Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Specificity and Generalizability of Cognitive Remediation and Functional Skills Training in Schizophrenia

Resource links provided by NLM:

U.S. FDA Resources

Further study details as provided by National Alliance for Research on Schizophrenia and Depression:

Primary Outcome Measures:
  • neurocognition [ Time Frame: 12 weeks ] [ Designated as safety issue: No ]

Secondary Outcome Measures:
  • functional competence [ Time Frame: 12 weeks ] [ Designated as safety issue: No ]
    performance-based measures of functional and social competence

  • neurocognition [ Time Frame: 24 weeks ] [ Designated as safety issue: No ]
  • neurocognition [ Time Frame: 36 weeks ] [ Designated as safety issue: No ]
  • functional competence [ Time Frame: 24 weeks ] [ Designated as safety issue: No ]
  • functional competence [ Time Frame: 36 weeks ] [ Designated as safety issue: No ]

Estimated Enrollment: 75
Study Start Date: July 2007
Estimated Study Completion Date: September 2010
Estimated Primary Completion Date: August 2010 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Cognitive remediation
Cognitive remediation
 Behavioral: Cognitive Remediation
Computer-based, therapist-lead cognitive remediation
Active Comparator: Functional Adaptive Skills Training
Functional and social skills group treatment
 Behavioral: FAST
Functional adaptive skills training. Group treatment to foster the acquisition of social and adaptive skills
Active Comparator: Combined Treatment
Combined cognitive remediation and functional adaptive skills training
 Behavioral: Cognitive Remediation
Computer-based, therapist-lead cognitive remediation
Behavioral: FAST
Functional adaptive skills training. Group treatment to foster the acquisition of social and adaptive skills

  Eligibility

Ages Eligible for Study:   18 Years to 65 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Diagnosis of schizophrenia or schizoaffective disorder
  • Enrolled in outpatient mental health care
  • Reading level of 6th grade or higher
  • English speaking

Exclusion Criteria:

  • Medical conditions known to affect cognition
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01175642

Contacts
Contact: Christopher R Bowie, PhD 613-533-3347 christopher.bowie@queensu.ca

Locations
Canada, Ontario
Queen's University Recruiting
Kingston, Ontario, Canada, K7L 3N6
Sponsors and Collaborators
National Alliance for Research on Schizophrenia and Depression
Investigators
Principal Investigator: Christopher R Bowie, PhD Queen's University
  More Information

No publications provided by National Alliance for Research on Schizophrenia and Depression

Additional publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):

Responsible Party: Christopher R. Bowie, Queen's University
ClinicalTrials.gov Identifier: NCT01175642     History of Changes
Other Study ID Numbers: PSYC-085-08
Study First Received: August 3, 2010
Last Updated: August 4, 2010
Health Authority: Canada: Ethics Review Committee

Keywords provided by National Alliance for Research on Schizophrenia and Depression:
Schizophrenia
Psychosis
Schizoaffective Disorder

Additional relevant MeSH terms:
Psychotic Disorders
Schizophrenia
Schizophrenia and Disorders with Psychotic Features
Mental Disorders

ClinicalTrials.gov processed this record on May 22, 2013