Trends Over Time (1990-2010) of Diarrhoea-related Hospitalizations and Deaths in Children < 5 Years of Age in Brazil
This study aims at collecting data to obtain baseline incidence and monitor trends over time in hospitalizations and deaths from all cause gastroenteritis in children <5 years of age, before and after implementation of Rotarix™ universal mass vaccination in Brazil.
|Study Design:||Observational Model: Ecologic or Community
Time Perspective: Retrospective
|Official Title:||Time Trend Analysis of Diarrhea-related Hospitalizations and Deaths in Children < 5 Years of Age in Brazil, 1990-2010|
- Occurrence of all cause gastroenteritis related hospital discharges and deaths [ Time Frame: In post vaccine introduction period compared to pre-vaccination period (gastroenteritis related hospital discharges from 1998 to 2010, gastroenteritis related deaths from 1990 to 2009) ] [ Designated as safety issue: No ]
- Occurrence of all cause gastroenteritis related hospital discharges and hospital deaths by year, region and age groups [ Time Frame: From 1998 to 2010 ] [ Designated as safety issue: No ]
- Occurrence of all cause gastroenteritis related deaths by year, region and age groups [ Time Frame: From 1990 to 2009 ] [ Designated as safety issue: No ]
|Study Start Date:||December 2008|
|Study Completion Date:||June 2012|
|Primary Completion Date:||June 2012 (Final data collection date for primary outcome measure)|
All children suffering with gastroenteritis
Other: Database analysis
Review and collect data from database
In this study baseline gastroenteritis related hospital discharges and mortality data from the Ministry of Health databases (DATASUS) will be compared to the current data after introduction of Rotarix™.