Persistence of Rabies Antibody 1-5 Years After the Post-exposure Prophylaxis With Vero Cell Antirabies Vaccine and Antibody Response to a Single Booster Dose
This study is to investigate the persistence of rabies Chinese manufactured antibody 1-5 years after the post-exposure prophylaxis with vero cell antirabies vaccine and antibody response to a single booster dose. A total of 160 subjects would be enrolled. These subjects were all administered ChengDa antirabies vaccine from 2005 to 2009. After informed consent is obtained, these subjects would be tested for their antirabies antibody titer and given a single booster dose. Seven and 14 days later, the investigators would re-evaluate the antibody titer.
|Study Design:||Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Health Services Research
|Official Title:||Persistence of Rabies Antibody 1-5 Years After the Post-exposure Prophylaxis With Vero Cell Antirabies Vaccine and Antibody Response to a Single Booster Dose|
- Rabies antibody titer [ Time Frame: 6 months ] [ Designated as safety issue: No ]We test the antirabies antibody titer before and after the single booster dose
|Study Start Date:||May 2010|
|Estimated Study Completion Date:||September 2010|
|Estimated Primary Completion Date:||August 2010 (Final data collection date for primary outcome measure)|
Experimental: Post vaccination
All the subjects had been vaccinated with antirabies vaccine.
Biological: Rabies vaccine, manufactured by ChengDa
1 dose before the antibody is tested
Other Name: ChengDa Speeda