Use of Laser Speckle to Study Post Occlusive Reactive Hyperhemia in Healthy Subjects (SpeckleShake)

The recruitment status of this study is unknown because the information has not been verified recently.
Verified June 2012 by University Hospital, Angers.
Recruitment status was  Recruiting
Sponsor:
Information provided by (Responsible Party):
University Hospital, Angers
ClinicalTrials.gov Identifier:
NCT01169974
First received: July 23, 2010
Last updated: June 28, 2012
Last verified: June 2012
  Purpose

The investigators aim to test the hypothesis that Laser speckle contrast imaging allows for the measurement of cutaneous blood flow following various durations of tourniquet ischemia.


Condition Intervention
Microcirculation
Other: tourniquet ischemia

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Evaluation Chez Des Sujets Volontaires Sains de l'ischémie-reperfusion cutanée

Further study details as provided by University Hospital, Angers:

Primary Outcome Measures:
  • Laser speckle [ Time Frame: with 2 minutes of ischemia ] [ Designated as safety issue: No ]
    Peak value of laser speckle signal


Estimated Enrollment: 30
Study Start Date: July 2010
Estimated Study Completion Date: October 2012
Estimated Primary Completion Date: September 2012 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
healthy volunteers Other: tourniquet ischemia
Recording of cutaneous blood flow on the forearm at rest before and following tourniquet ischemias of 1 , 2 & 3 minutes
Other Names:
  • Laser doppler flowmetry
  • Transcutaneous oxygen pressure
  • Near infra-red spectrometry
  • Plethysmography

Detailed Description:

Ischemia and post occlusive reactive hyperemia in the skin is tested in healthy normal subjects for tourniquet ischemias of 1, 2 & 3 minutes at rest.

  Eligibility

Ages Eligible for Study:   18 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

healthy volunteers

Criteria

Inclusion Criteria:

  • Healthy volunteers
  • Affiliation to the French health system

Exclusion Criteria:

  • Any disease or chronic treatment
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01169974

Contacts
Contact: guillaume Mahe, MD +33 241363689

Locations
France
University hospital Recruiting
Angers, France
Contact: Guillaume Mahe, MD    +33 241363689      
Sub-Investigator: Pierre Abraham         
Sponsors and Collaborators
University Hospital, Angers
Investigators
Principal Investigator: Guillaume Mahe University Hospital in Angers
  More Information

No publications provided

Responsible Party: University Hospital, Angers
ClinicalTrials.gov Identifier: NCT01169974     History of Changes
Other Study ID Numbers: CHU P 2010-18
Study First Received: July 23, 2010
Last Updated: June 28, 2012
Health Authority: France: Ministry of Health

Keywords provided by University Hospital, Angers:
Microcirculation
laser flowmetry
Skin
Physiology

ClinicalTrials.gov processed this record on September 18, 2014