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Ability of Modulated Imaging and Laser Speckle Imaging to Determine Burn Wound Severity and Healing Potential

This study is enrolling participants by invitation only.
Sponsor:
Information provided by (Responsible Party):
Montana Compton, University of California, Irvine
ClinicalTrials.gov Identifier:
NCT01166893
First received: July 20, 2010
Last updated: January 7, 2013
Last verified: January 2013
History of Changes
  Purpose

Currently, the primary method of determining burn depth is clinical assessment. Unfortunately, studies demonstrate that even experienced burn surgeons are accurate in their initial assessment in only 60-80% of wounds1. Underestimation of burn wound depth will lead to a delay in diagnosis, prolonged hospitalization, prolonged provision of painful costly procedures, and potentially hypertrophic and/keloid scarring with functional and cosmetic deformity. Overestimation of burn wound depth may lead to surgical wound excision with skin grafting that is potentially unnecessary.


Condition Intervention
Skin Burn Multiple
 Device: Modulated Imaging and Laser Speckle Imaging

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Ability of Modulated Imaging and Laser Speckle Imaging to Determine Burn Wound Severity and Healing Potential

Resource links provided by NLM:

MedlinePlus related topics: Burns
U.S. FDA Resources

Further study details as provided by University of California, Irvine:

Primary Outcome Measures:
  • wound healing [ Time Frame: 1 day ] [ Designated as safety issue: No ]

Estimated Enrollment: 200
Study Start Date: March 2010
Estimated Study Completion Date: February 2015
Estimated Primary Completion Date: February 2015 (Final data collection date for primary outcome measure)
Intervention Details:
    Device: Modulated Imaging and Laser Speckle Imaging
    wound healing
    Other Name: MI-LSI developed at UCI Beckman Laser Institute
Detailed Description:

Modulating Imaging is a noninvasive optical modality designed to create a 3-dimensional differential diagram of the metabolic functions of the tissue. Laser Speckle Imaging is a noninvasive optical modality designed to create a dynamic map of blood flow to an area of interest. Both have previously been used to on other disease entities to estimate the extent of pathology.

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

primary care clinic, community sample

Criteria

Inclusion Criteria:

  1. Male / female all age
  2. Subjects is an inpatient at UCIMC with burn wound

Exclusion Criteria:

  1. Subjects cannot lied flat and still for the duration of the imaging (5 to 10 minutes)
  2. Subjects pregnant.
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT01166893

Locations
United States, California
UCIMC
Orange, California, United States, 92868
Sponsors and Collaborators
Montana Compton
Investigators
Principal Investigator: Anthony Durkin, PhD Beckman Laser Institute University of California Irvine
  More Information

No publications provided

Responsible Party: Montana Compton, Administrative Nurse Research Coordinator Beckman Laser Institute, University of California, Irvine
ClinicalTrials.gov Identifier: NCT01166893     History of Changes
Other Study ID Numbers: LAMMP-30139; HS#2010-7322
Study First Received: July 20, 2010
Last Updated: January 7, 2013
Health Authority: United States: Institutional Review Board

Keywords provided by University of California, Irvine:
burn wound

Additional relevant MeSH terms:
Burns
Wounds and Injuries

ClinicalTrials.gov processed this record on June 18, 2013