Change in Gastrointestinal Complaints After Switch From Oral Parkinson's Disease Treatment to Neupro® Transdermal Patch (NON-GI)

• Change From Baseline to Visit 3 in the Assessment of Intensity of Gastrointestinal (GI) Complaints for Any Reason as Per Visual Analogue Scale (VAS) [ Time Frame: From Baseline to Visit 3 (approximately 6 weeks) ] [ Designated as safety issue: No ]
  Patients were asked to classify the intensity of their GI complaints on a scale ranging from 0 (no complaints) to 100 (extremely severe complaints). Negative values indicate an improvement from Baseline to Visit 3 with larger negative values showing a better improvement.
  
  
• Change From Baseline to Visit 3 in the Sum Score of Gastrointestinal (GI) Complaints [ Time Frame: From Baseline to Visit 3 (approximately 6 weeks) ] [ Designated as safety issue: No ]

  Sum score of GI complaints was calculated from frequency and intensity of the complaints. The intensity of GI complaints during the last week ranges from 0 (no complaints) to 3 (severe) and the frequency of these complaints during the last week ranges from 0 (never) to 4 (every day).

  For each of the seven GI complaints assessed at a visit (swallowing disorders, heartburn, feeling of fullness, nausea, vomiting, abdominal pain, and diarrhea), intensity and frequency were multiplied to achieve individual item scores of GI complaints (range: 0 - 12).

  Finally, the sum score of GI complaints per visit was calculated by accumulating 6 of the 7 item scores (excluding swallowing disorders, which was recorded at Baseline only) for patients with valid values in each score (range: 0 - 72). Negative values indicate an improvement from Baseline to Visit 3 with larger negative values showing a better improvement.

  
  
• Assessment of Patient Satisfaction Referring to Gastrointestinal (GI) Complaints Following Treatment Switch to Neupro® at Visit 2 [ Time Frame: At Visit 2 (after approximately 2-4 weeks) ] [ Designated as safety issue: No ]

  Patient satisfaction referring to GI complaints is classified into 5 categories:

  • Missing
  • Very satisfied
  • Satisfied
  • Moderately satisfied
  • Not satisfied.
  
  
• Assessment of Patient Satisfaction Referring to Gastrointestinal (GI) Complaints Following Treatment Switch to Neupro® at Visit 3 [ Time Frame: At Visit 3 (after approximately 6 weeks) ] [ Designated as safety issue: No ]

  Patient satisfaction referring to GI complaints is classified into 5 categories:

  • Missing
  • Very satisfied
  • Satisfied
  • Moderately satisfied
  • Not satisfied.
  
  

Routine treatment as per approved label in Europe in accordance with the terms of the local marketing authorization for Neupro®.