Exercise and Cognitive Training in Parkinson's Disease - Full Text View

Sponsor:	Department of Veterans Affairs
Collaborator:	University of Maryland
Information provided by (Responsible Party):	Department of Veterans Affairs
ClinicalTrials.gov Identifier:	NCT01156714

Purpose

This study looks at whether treadmill exercise and memory training on a computer can improve memory in Parkinson's Disease

Condition	Intervention
Parkinson's Disease	Behavioral: treadmill training Behavioral: computerized memory training

Study Type:	Interventional
Study Design:	Allocation: Randomized Endpoint Classification: Efficacy Study Intervention Model: Parallel Assignment Masking: Open Label Primary Purpose: Treatment
Official Title:	Effects of Exercise and Cognitive Training on Executive Function in Parkinson's Disease

Resource links provided by NLM:

Genetics Home Reference related topics: familial paroxysmal nonkinesigenic dyskinesia Perry syndrome

MedlinePlus related topics: Exercise and Physical Fitness Memory Parkinson's Disease

U.S. FDA Resources

Further study details as provided by Department of Veterans Affairs:

Primary Outcome Measures:

Improved executive function on a neuropsychological test battery [ Time Frame: 3 months ] [ Designated as safety issue: No ]

Secondary Outcome Measures:

Improved dual task ability [ Time Frame: 3 months ] [ Designated as safety issue: No ]
Improvement in instrumental activities of daily living [ Time Frame: 3 months ] [ Designated as safety issue: No ]

Estimated Enrollment:	121
Study Start Date:	October 2010
Estimated Study Completion Date:	July 2014
Estimated Primary Completion Date:	December 2013 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
1 Treadmill training with aerobic exercise	Behavioral: treadmill training walk on treadmill for aerobic exercise
2 Memory training with computerized memory program	Behavioral: computerized memory training memory testing and training on computer program
3 Combination of treadmill training and computerized memory program	Behavioral: treadmill training walk on treadmill for aerobic exercise Behavioral: computerized memory training memory testing and training on computer program

Detailed Description:

Executive memory loss is common in Parkinson's Disease (PD). There is no known treatment for it. This study looks at whether executive memory function is improved in PD by either treadmill aerobic training, computerized memory training, or a combination of both.

Eligibility

Ages Eligible for Study:	40 Years to 90 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Parkinson's disease stage 1-3 Hoehn and Yahr Balance problems

Exclusion Criteria:

unstable medical illness unstable psychiatric illness exercising too much on own doing computerized memory training on own

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT01156714

Contacts

Contact: Terra Hill	(410) 328-5800	thill@som.umaryland.edu
Contact: Sara E Carney, MS BA	(410) 605-7000 ext 4858	sara.carney@va.gov

Locations

United States, Maryland
VA Maryland Health Care System, Baltimore	Recruiting
Baltimore, Maryland, United States, 21201
Contact: Terra Hill 410-328-5800 thill@som.umaryland.edu
Principal Investigator: Karen E Anderson, MD

Sponsors and Collaborators

Department of Veterans Affairs

University of Maryland

Investigators

Principal Investigator:

Karen E Anderson, MD

VA Maryland Health Care System, Baltimore

More Information

No publications provided

Responsible Party:	Department of Veterans Affairs
ClinicalTrials.gov Identifier:	NCT01156714 History of Changes
Other Study ID Numbers:	E7158-R
Study First Received:	March 11, 2010
Last Updated:	March 27, 2012
Health Authority:	United States: Federal Government

Keywords provided by Department of Veterans Affairs:

Parkinson's disease
Treadmill training
Exercise

Cognitive Training
executive function
dual task

Additional relevant MeSH terms:

Parkinson Disease
Parkinsonian Disorders
Basal Ganglia Diseases
Brain Diseases

Central Nervous System Diseases
Nervous System Diseases
Movement Disorders
Neurodegenerative Diseases

ClinicalTrials.gov processed this record on May 24, 2012