The Evaluation of Therapeutic Efficacy on the Integrated Group Psychotherapy for Patients With Schizophrenia
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Purpose
Although the patients with schizophrenia can be treated with new generation of antipsychotics medication, additional approaches are necessary to improve schizophrenics' cognitive functions, interpersonal relationships as well as social adjustment. When some of patients return to community, they expose to practical pressure that contribute to worsen and relapse of disease. That further damages patient's cognitive functions. Integrated Psychological Therapy(IPT) on treating schizophrenia has dramatic improvement in recent years; it has formed structured treatment gradually on relieving illusion, hallucination as well as negative symptoms. This study aims at conducting 12-week structured IPT group therapy. The intended subjects are patients, met with DSM-Ⅳ-TR diagnosis of schizophrenia, from community, outpatient and inpatient service. The overall treatments are designed to provide 1-2 hours weekly group therapy which focuses on relieving illusions, hallucination, and negative symptoms. Patients' cognitive functions, ability of emotional adjustment and interpersonal relationship would be evaluated in pre-test and post-test to indicate whether the significant difference exists. There is a controlled group, in which patients who still receive treatment as usual (TAU). The study also compares the evaluation results between IPT group and TAU group, hoping to develop the therapeutic framework for Taiwan people with schizophrenia.
| Condition | Intervention |
|---|---|
|
Schizophrenia |
Behavioral: Group Psychotherapy |
| Study Type: | Interventional |
| Study Design: | Allocation: Randomized Intervention Model: Parallel Assignment Masking: Open Label Primary Purpose: Treatment |
| Official Title: | Department of Psychiatry of NTUH Yun-Lin Branch |
- re-hospitalization rate [ Time Frame: after 3 months of the group psychotherapy ] [ Designated as safety issue: No ]acute symptom relapse and needed to be admitted to the acute ward
- Cognitive functions, ability of emotional adjustment, and interpersonal relationship [ Time Frame: 12 months of the group tpsychotherapy ] [ Designated as safety issue: No ]The tests of psychiatric symptoms, cognitive test, anxiety, depression, interpsersonal skill, and emotional adjustment Add Secondary Outcome Measure:The Positive and Negative Syndrome Scale, Beck depression scale, Beck anxiety scale, Beck suicial ideation scale, Cognitive tests (visual spatial test), CPT-IP for attention test
- The Positive and Negative Syndrome Scale, Beck depression scale, Beck anxiety scale, Beck suicial ideation scale, Cognitive tests (visual spatial test), CPT-IP for attention test [ Time Frame: 12 months of the group psychotherapy ] [ Designated as safety issue: No ]The Positive and Negative Syndrome Scale for psychiatric symptoms, Beck depression scale for depression symptoms, Beck anxiety scale for anxiety symptoms, Beck suicial ideation scale for suicidal ideation evalution Cognitive tests (visual spatial test), CPT-IP for attention test for cognitive function
| Enrollment: | 50 |
| Study Start Date: | May 2010 |
| Study Completion Date: | May 2011 |
| Primary Completion Date: | May 2011 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
|
Arm
There is no arm in this study.
|
Behavioral: Group Psychotherapy
integrated group psychotherapy, including the interpersonal and cognitive group therapy
|
Eligibility| Ages Eligible for Study: | 18 Years to 80 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- schizophrenia,
- can concentrate in group for 30 minutes.
Exclusion Criteria:
- substance abuse (alcohol, illegal medication),
- self harm history.
Contacts and Locations| Taiwan | |
| National Taiwan University Hospital Yun-Lin Branch | |
| Yun-lin, Taiwan, 64001 | |
| Study Director: | Li-Ren Chang, MD | Department of Psychiatry in National Taiwan University Hospital Yun-Lin Branch |
More Information
No publications provided
| Responsible Party: | National Taiwan University Hospital |
| ClinicalTrials.gov Identifier: | NCT01139099 History of Changes |
| Other Study ID Numbers: | 201003068R |
| Study First Received: | June 7, 2010 |
| Last Updated: | December 26, 2012 |
| Health Authority: | Taiwan: Department of Health |
Additional relevant MeSH terms:
|
Schizophrenia Schizophrenia and Disorders with Psychotic Features Mental Disorders |
ClinicalTrials.gov processed this record on June 18, 2013